System drastically cuts down botulism detection time

Washington, D.C. -- One of the most lethal substances in the world -- botulism -- can be detected using special systems in about 2025 minutes. Now, researchers at DOE's Pacific Northwest National Laboratory can detect its presence in five minutes, using the lab's successful Biodetection Enabling Analyte Delivery System, or BEADS combined with optical detection.

The detection system includes three critical components. First, BEADS isolates the toxin from environmental samples. Next, an antibody is used to purify and concentrate the pathogen or toxin to enable accurate and sensitive detection. Finally, a second antibody, called a reporter antibody, labeled with a fluorescent dye or a fluorescent quantum dot binds to a different region on the toxin or pathogen. The fluorescence of the quantum dot is measured on the bead and can quantify the concentration of the toxin.

The BEADS system has been commercially licensed to a few companies. In addition to detecting botulinum, the system can be tailored to detect multiple pathogens or toxins, such as E. coli, salmonella and ricin, simultaneously.


Contact: Greg Koller
DOE/Pacific Northwest National Laboratory

Page: 1

Related biology news :

1. System to analyze beating heart stem cells could lead to heart attack treatments
2. UCLAs California NanoSystems Institute partners with Abraxis BioScience
3. DOE JGI upgrades its Microbial Genome Analysis System
4. Systems characterization of cell surface receptors
5. Kent State University and Summa Health System receive NIH grant to study prehypertension
6. New Geisinger Health System building green Center for Health Research
7. DOE JGI releases enhanced Genome Data Management System IMG 2.1 marking 2-year anniversary
8. Virginia Techs System X supercomputer provides super tool for simulation of cell division
9. DOE JGI upgrades IMG/M -- the Metagenomics Data Management & Analysis System
10. BioMed Central launches BMC Systems Biology, a new open access journal
11. CellSearch System cleared for monitoring metastatic breast cancer

Post Your Comments:

(Date:8/19/2019)... ... August 19, 2019 , ... Since ... use of ultra-thin two dimensional slices which are placed on microscope slides, stained ... complex tissues and complicated features such as vasculature and thus researchers in the ...
(Date:8/15/2019)... ... ... Deep Science Ventures (DSV), a new paradigm for applied science, today announced ... 100 companies over the next 10 years to address the urgent need for new ... was founded to create a better method for launching science companies; one that takes ...
(Date:8/15/2019)... ... , ... Serialization deadlines in the US and European Union ... becomes fully applied in the United States in 2023, pharmaceutical companies are scrutinizing ... most regulations?including the Drug Supply Chain Security Act (DSCSA)?have required minimal system capabilities. ...
Breaking Biology News(10 mins):
(Date:8/15/2019)... ... August 15, 2019 , ... PathSensors announced today that Roger ... of the Institute of Food Technologists (IFT) Board of Directors, Illinois Institute of ... for Food Safety and Applied Nutrition (JIFSAN) Advisory Council and the University of ...
(Date:8/14/2019)... STATE COLLEGE, Pa. (PRWEB) , ... August 13, ... ... leader in nuclear receptor and in vitro toxicology testing solutions, announced the appointment ... of healthcare industry experience to the Board. , Mark McLoughlin will lend his ...
(Date:8/14/2019)... ... August 13, 2019 , ... ... prepackaged mobile phases for QC laboratories. After gaining a few significant clients, Lifecycle ... approach into a valued supplier of manufacturing processing solutions, including reagents for tissue ...
(Date:8/8/2019)... , ... August 08, 2019 , ... ... Agents for sales and service organizations, today announced that the company’s Studio ... Award for the IVA market . Inference will officially accept the award at ...
Breaking Biology Technology:
Cached News: