HOME >> BIOLOGY >> NEWS
Technique makes it easier to see mouse embryo in all its glory

A fast, high-resolution, 3D mouse embryo visualization technique developed by collaborators at the University of Texas Health Science Center at San Antonio and the University of Utah will revolutionize the way birth defects and cancer genes are studied in animal models. That's the prediction of the researchers in an article to be published online in PLoS Genetics on April 28, a peer-reviewed, open-access journal from the Public Library of Science.

The new tool, called Virtual Histology, has already boosted the researchers' ability to study the mouse embryo and more rapidly focus on abnormalities of development, including childhood cancers. Birth defects are diagnosed in 150,000 babies in the U.S. annually. Suspected causes are genetic abnormalities, environmental insults, and drug and chemical exposures.

Charles Keller, M.D., assistant professor at the Children's Cancer Research Institute (CCRI) at The University of Texas Health Science Center at San Antonio, is studying ways to improve treatment of two types of childhood cancers '" brain tumors called medulloblastomas and muscle tumors called alveolar rhabdomyosarcomas. Dr. Keller, a pediatric oncologist, moved to the CCRI from the University of Utah in 2005, and continues his collaborations with engineers and computer scientists at Utah's Scientific Computing and Imaging Institute. Dr. Keller routinely works with mouse embryos in trying to understand the role of developmentally regulated genes in the types of cancers that children sometimes acquire. The study of genetically modified embryos and their birth defects is usually a slow and laborious process, but Dr. Keller and colleagues have found a way to make the analysis much faster '" and more accurate.

Traditional histology involves embedding embryos in wax, thinly slicing the wax and delicately placing it on slides, staining the sections and viewing slides under the microscope, then mentally reconstructing the three-dimensional asp
'"/>

Contact: Will Sansom
sansom@uthscsa.edu
210-567-2579
Public Library of Science
27-Apr-2006


Page: 1 2 3

Related biology news :

1. Technique quickly identifies bacteria for food safety, health care and homeland security
2. Technique used commonly in physics finds application in neuroscience
3. Technique offers new view of dynamic biological landscape
4. Technique provides new look on response of diseased canine heart
5. Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
6. Technique for genetically modifying blood stem cells brings cure for blood diseases closer
7. Altering a protein makes mice less fearful
8. Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
9. Book makes case for using evolution in everyday life
10. Dartmouth professor makes case for ethically universal stem cell lines
11. A nurse makes the decision on who will live

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/28/2018)... ... July 28, 2018 , ... ... Kong Polytechnic University (PolyU), has been honoured with the International Association for Wind ... of wind engineering and bridge engineering in research, education, and application. Professor Xu ...
(Date:7/26/2018)... ... July 26, 2018 , ... Shirley Holmlund, an evidence-based ... biofield energy healing treated Vitamin D3 on the strength and health of bones. ... 290% improvement in bone mineralization and over 100% increase in ALP, a bone-specific ...
(Date:7/25/2018)... ... July 25, 2018 , ... A pioneering Duchenne muscular dystrophy clinical trial ... annual Mt. Kinabalu climb to raising awareness of the need to enroll patients. ... with patients and families willing to participate in a clinical trial,” said Catherine Jayasuriya, ...
Breaking Biology News(10 mins):
(Date:8/9/2018)... ... August 09, 2018 , ... Simpson Gumpertz & Heger (SGH) ... building owners and managers for a full-day discussion on health care and life ... Boston for the first time on Thursday, 13 September 2018, at Harvard Medical ...
(Date:8/7/2018)... ... 06, 2018 , ... PetPace , the makers of a smart health-monitoring ... announced the launch of a groundbreaking study to identify and eventually predict problems and ... of pregnant dogs sponsored by PetPace and conducted by Dr. Smadar Tal, DVM, DACT, ...
(Date:7/31/2018)... ... July 31, 2018 , ... Leading regenerative ... methods for extracting and using adipose tissue-derived stem cells to treat or prevent ... While this patent covers Canada specifically, VetStem has been issued similar patents that ...
(Date:7/31/2018)... ... 31, 2018 , ... Mahoney Environmental , a leading ... new website. The new website has been designed with improved functionality and navigation, ... Innovative to build a website created for the customer. The newly redesigned site ...
Breaking Biology Technology:
Cached News: