Abstracts for all presentations may be accessed through a complete searchable online program at http://www.faseb.org/meetings/eb2005/call/default.htm covering both IUPS and Experimental Biology 2005, which is being held concurrently.
"Temperature-dependent cadmium effects on whole animal and mitochondrial metabolism of the eastern oyster Crassostrea virginica."
Gisela Lannig, Inna Sokolova. Biological Department, University of North Carolina at Charlotte. Physiology 138.12
The researchers found that increased susceptibility of oysters to trace metal pollution at high temperature suggests that global warming can post a deadly threat for populations in polluted areas because previously non-toxic concentrations may become toxic and fatal with warming. Next step will be to study to what extent metal pollution reduces temperature tolerance limits of oysters and to apply that knowledge to study other ectothermic animals.
Supported by the Alexander von Humboldt Foundation and National Science Foundation.
"Maturation and functional restoration of DeltaF508CFTR by its subdomains in cystic fibrosis airway cells."
Fei Sun, Steven B Condliff, Carol A Bertrand, Zhibao Mi, Joseph M Pilewski, Paul D Robbins, Robert J Bridges, Raymond A Frizzell. Cell Biology and Physiology, University of Pittsburgh. Physiology 349.3. Featured topic 340: "Molecular basis of epithelial disease."
Cystic fibrosis is the most common fatal genetic disease among Caucasians, with about 30,000 CF patients in North America. Researchers tested the notion that introducing a fragment of mutant CFTR (cystic fibrosis transmembrane conductance regulator) would compe