"Dietary interventions reduce muscle weakness in unloaded muscle."
Sandrine Arbogast1, Ann R. Kennedy2, Michael B. Reid1. 1Dept of Physiology, University of Kentucky, 2Dept of Radiation Oncology, University of Pennsylvania. Physiology 347.5. Featured topic session #659: "Mosso and muscle fatigue: 116 years after the 1st Congress of Physiology."
Whether it's an astronaut in space for a long time or an elderly person recovering from hip surgery, leg muscles get smaller and weaker, and the person has difficulty standing or walking. The muscle wasting is associated with an increase in free radical production and protein breakdown. Using mice unable to put force on their hind legs, researchers tested two diets: 1% Bowman-Birk inhibitor concentrate (a protease inhibitor made from soybeans) and the second a mixture of antioxidants. They found that while neither diet prevented muscle wasting, both diets lessened the weakness caused by the "unloading."
Funding: National Space Biomedical Research Institute and NIH grant.
"Expression profile of EphA receptors after spinal cord injury in adult rats."
Lillian Cruz-Orengo1, Johnny Davis Figueroa1, Ixane Velzquez1, Margarita Irizarry-Ramrez1, Christopher A Willson2, Hope Jones2, Scott R Whittemore2, Jorge David Miranda1. 1Physiology, UPR School of Medicine, San Juan, Puerto Rico, 2Neurological Surgery, University of Louisville School of Medicine, Kentucky Spinal Cord Injury Research Center Neurological Surgery. Physiology 924.3. Featured topic session #895: "Long-term plasticity and SCI."
Researchers are looking at molecular activities that
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4-Apr-2005