HOME >> BIOLOGY >> NEWS
Tiny scaffolding allows stem cells to become working fat cells

r) across, and provide tensile strength to support the growing tissue," Kniss said. The researchers then "seeded" that scaffolding with cells called pre-adipocytes cells that had begun their transformation from stem cells. "They just needed to be tweaked with a cocktail of hormones for them to evolve into fat cells," he said.

Kniss said that the transformation into bona fide fat cells took about two weeks to complete. At that point, the cells were able to absorb lipids a hallmark task of fat cells.

Researchers were able to extract RNA from the cells, just as they can from naturally occurring fat cells, and from that proved that the cells expressed the normally expected array of genes, and subsequent proteins and did so as well as occurs in normal tissue. So far, the researchers have kept the cells alive and thriving for several months and hope to maintain them for up to a year.

"We know that the environment in which a community of cells finds itself has a great deal of influence on the biology underway within those cells," Kniss said. "And that biology is always translated into changes in gene expression and assemblies of proteins." That is why the three-dimensional scaffolding for cell growth in the laboratory is so important.

The researchers' focus on fat cells as a test bed for this approach to cell growth offers important medical potential. While experts once thought a persons number of fat cells was set at birth, they now know individuals can either lose existing fat cells or grow new ones. And aside from the implications for dieting and obesity, a person's population of fat cells has other vital roles.

Fat cells extract lipids, or fatty acids, from the bloodstream. They also become a huge reservoir for glucose as well, and play a role in insulins ability to effectively convert glucose into energy.

"If we could learn how to control fat formation in the body, then we could keep people leaner, lowering their
'"/>

Contact: Douglas Kniss
kniss.1@osu.edu
614-293-4496
Ohio State University
22-Mar-2005


Page: 1 2 3

Related biology news :

1. Bedsores and bald hides: Novel roles revealed for a scaffolding protein
2. Presence of wolves allows aspen recovery in Yellowstone
3. Cannibalism of the young allows individual fish to specialize
4. Social tolerance allows bonobos to outperform chimpanzees on a cooperative task
5. Expedition allows teachers to participate in polar research
6. Remarkable physiology allows crucian carp to survive months without oxygen
7. 100,000 year-old DNA sequence allows new look at Neandertals genetic diversity
8. New approach allows closer look at smoker lungs
9. Why nerve cells work faster than the theory allows
10. A new tree of life allows a closer look at the origin of species
11. Parachuting allows krill to eat and run

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2017)... 27, 2017  Catholic Health Services (CHS) has ... Society (HIMSS) Analytics for achieving Stage 6 on ... . In addition, CHS previously earned a place ... an electronic medical record (EMR). "HIMSS ... of EMR usage in an outpatient setting.  This ...
(Date:3/24/2017)... The Controller General of Immigration from Maldives Mr. ... have received the prestigious international IAIR Award for the most innovative ... ... Maldives Immigration ... Algeen (small picture on the right) have received the IAIR award for ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access System ... over the next decade to reach approximately $1,580 million by 2025. ... forecasts for all the given segments on global as well as ...
Breaking Biology News(10 mins):
(Date:3/27/2017)... , March 27, 2017 Neurotrope, ... novel therapies for neurodegenerative diseases, including Alzheimer,s disease, ... its application to list the Company,s common stock ... by The NASDAQ Stock Market, a unit of ... listing, Neurotrope will ring the Opening Bell at the ...
(Date:3/24/2017)... DUBLIN , Mar. 24, 2017 Research ... Stem Cell (hESC) Research - Global Strategic Business Report" report ... ... Cell (hESC) Research in US$ Million. Annual estimates and forecasts are ... are derived from primary and secondary research. The ...
(Date:3/24/2017)...   Sienna Biopharmaceuticals, Inc. , a privately held, ... Richard Peterson will join the company as ... who brings more than two decades of global financial ... retiring at the end of April but will continue ... Sienna from Novan, Inc., where he served as Chief ...
(Date:3/23/2017)... , ... March 23, 2017 , ... Lajollacooks4u is proud to announce it has become ... hosted corporate cooking challenges for companies around the world, such as Illumina, HP and Qualcomm, ... the reason for its increasing popularity is due to its new team building format, a ...
Breaking Biology Technology:
Cached News: