HOME >> BIOLOGY >> NEWS
Tips from the journals of the American Society for Microbiology

Ulcer Drug Inhibits Gum Disease in Rabbits

Researchers from Boston University School of Medicine have discovered that topical application of an ulcer drug to teeth may help prevent gum disease. Their findings appear in the April 2006 issue of the journal Infection and Immunity.

Periodontitis (gum disease) occurs when the bacterium Porphyromonas gingivalis accumulates on the tooth's surface causing inflammatory disease which leads to loss of connective tissue and bone. This disease affects tens of millions of people in the U.S. alone, emphasizing the importance of effective preventative care and treatment method.

Cimetidine is a powerful H2 receptor antagonist originally designed to treat ulcers by blocking the acid producing cells in the stomach. In the study three groups of rabbits were simultaneously induced with experimental periodontitis using P. gingivalis and treated with varying levels of topically applied cimetidine three times a week over a six-week period. Results showed that topical application of cimetidine at all concentrations inhibited inflammation and bone loss by approximately 90%.

"The findings of this study provide morphological and histological evidence that topically active cimetidine is a potent inhibitor of P. gingivalis-elicited periodontal inflammation, arresting and/or preventing tissue destruction and influencing cell populations present in the inflammatory cell infiltrate," say the researchers.

(H. Hasturk, A. Kantarci, N. Ebrahimi, C. Andry, M. Holick, V.L. Jones, T.E. Van Dyke. 2006. Topical H2 antagonist prevents periodontitis in a rabbit model. Infection and Immunity, 74. 4: 2402-2414.)

Artificial Illumination Using White or Green Light May Prevent Biofilm Formation on Artwork

Using white or green light to artificially illuminate artwork may prevent biofilm formation and surface deterioration, say researchers from Spain. They report their findings in t
'"/>

Contact: Carrie Patterson
cpatterson@asmusa.org
202-942-9389
American Society for Microbiology
14-Apr-2006


Page: 1 2 3

Related biology news :

1. Cluster of journals publish findings on dangerous parasite, Toxoplasma gondii
2. Tips from the journals of the American Society for Microbiology
3. Springer expands life science program with In Vitro journals
4. Tips from the journals of the American Society for Microbiology
5. Tips from the journals of the American Society for Microbiology
6. Impressive new Impact Factors for BioMed Centrals open-access journals
7. Tips from the journals of the American Society for Microbiology
8. Tips from the journals of the American Society for Microbiology
9. Tips from the journals of the American Society for Microbiology
10. Tips from the journals of the American Society for Microbiology
11. Tips from the journals of the American Society for Microbiology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... BROOKLYN, N.Y. , April 11, 2017 /PRNewswire-USNewswire/ ... identical fingerprints, but researchers at the New York ... University College of Engineering have found that partial ... fingerprint-based security systems used in mobile phones and ... previously thought. The vulnerability lies in ...
(Date:4/5/2017)... -- KEY FINDINGS The global market for ... of 25.76% during the forecast period of 2017-2025. The ... the growth of the stem cell market. ... INSIGHTS The global stem cell market is segmented on ... stem cell market of the product is segmented into ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
Breaking Biology News(10 mins):
(Date:6/27/2017)... ... 2017 , ... According to a recent report from the ... have negative short- or long-term effects on benthic communities. , The ESTCP ... at the Puget Sound Naval Shipyard & Intermediate Maintenance Facility in Bremerton, Washing. ...
(Date:6/26/2017)... ... June 26, 2017 , ... ... Kirkegaard, the former Associate Director of Product Development R&D at Allergan and CMC ... products at both start-up and established biopharma companies, has joined the firm as ...
(Date:6/26/2017)... ... , ... Two new members were elected to the University City Science Center’s ... President, J Nowak Strategy and Michele Masucci, Ph.D., Vice President for Research Administration at ... and Kenneth L. Kring, and re-election of David P. Holveck and Richard P. Jaffe, ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ken Hanson, a medical imaging research scientist at ... been selected as this year’s recipients of two top awards from SPIE, the ... with other honorees to accept their awards at a banquet in San Diego, California, ...
Breaking Biology Technology:
Cached News: