HOME >> BIOLOGY >> NEWS
Tips from the journals of the American Society for Microbiology

Ulcer Drug Inhibits Gum Disease in Rabbits

Researchers from Boston University School of Medicine have discovered that topical application of an ulcer drug to teeth may help prevent gum disease. Their findings appear in the April 2006 issue of the journal Infection and Immunity.

Periodontitis (gum disease) occurs when the bacterium Porphyromonas gingivalis accumulates on the tooth's surface causing inflammatory disease which leads to loss of connective tissue and bone. This disease affects tens of millions of people in the U.S. alone, emphasizing the importance of effective preventative care and treatment method.

Cimetidine is a powerful H2 receptor antagonist originally designed to treat ulcers by blocking the acid producing cells in the stomach. In the study three groups of rabbits were simultaneously induced with experimental periodontitis using P. gingivalis and treated with varying levels of topically applied cimetidine three times a week over a six-week period. Results showed that topical application of cimetidine at all concentrations inhibited inflammation and bone loss by approximately 90%.

"The findings of this study provide morphological and histological evidence that topically active cimetidine is a potent inhibitor of P. gingivalis-elicited periodontal inflammation, arresting and/or preventing tissue destruction and influencing cell populations present in the inflammatory cell infiltrate," say the researchers.

(H. Hasturk, A. Kantarci, N. Ebrahimi, C. Andry, M. Holick, V.L. Jones, T.E. Van Dyke. 2006. Topical H2 antagonist prevents periodontitis in a rabbit model. Infection and Immunity, 74. 4: 2402-2414.)

Artificial Illumination Using White or Green Light May Prevent Biofilm Formation on Artwork

Using white or green light to artificially illuminate artwork may prevent biofilm formation and surface deterioration, say researchers from Spain. They report their findings in t
'"/>

Contact: Carrie Patterson
cpatterson@asmusa.org
202-942-9389
American Society for Microbiology
14-Apr-2006


Page: 1 2 3

Related biology news :

1. Cluster of journals publish findings on dangerous parasite, Toxoplasma gondii
2. Tips from the journals of the American Society for Microbiology
3. Springer expands life science program with In Vitro journals
4. Tips from the journals of the American Society for Microbiology
5. Tips from the journals of the American Society for Microbiology
6. Impressive new Impact Factors for BioMed Centrals open-access journals
7. Tips from the journals of the American Society for Microbiology
8. Tips from the journals of the American Society for Microbiology
9. Tips from the journals of the American Society for Microbiology
10. Tips from the journals of the American Society for Microbiology
11. Tips from the journals of the American Society for Microbiology

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/1/2016)... 1, 2016 Favorable Government Initiatives ... and Criminal Identification to Boost Global Biometrics System Market ... TechSci Research report, " Global Biometrics Market By ... and Opportunities, 2011 - 2021", the global biometrics market ... on account of growing security concerns across various end ...
(Date:5/9/2016)... -- Elevay is currently known as the ... high net worth professionals seeking travel for work   ... there is still no substitute for a face-to-face meeting. ... deal with a firm handshake. This is why wealthy ... citizenship via investment programs like those offered by the ...
(Date:4/26/2016)... 27, 2016 Research and ... Biometrics Market 2016-2020"  report to their offering.  , ... The analysts forecast the global multimodal biometrics ... during the period 2016-2020.  Multimodal biometrics ... such as the healthcare, BFSI, transportation, automotive, and ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... Ginkgo Bioworks , a leading organism design company ... as one of the World Economic Forum,s Technology ... companies. Ginkgo Bioworks is engineering biology to manufacture ... the nutrition, health and consumer goods sectors. The ... Fortune 500 companies to design microbes for their ...
(Date:6/24/2016)... June 24, 2016 Epic Sciences unveiled ... cancers susceptible to PARP inhibitors by targeting homologous ... (CTCs). The new test has already been incorporated ... multiple cancer types. Over 230 clinical ... response pathways, including PARP, ATM, ATR, DNA-PK and ...
(Date:6/24/2016)... NC (PRWEB) , ... June 24, 2016 , ... Researchers ... the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are ... to read it now. , Diagnostic biomarkers are signposts in the blood, lung ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... announce the launch of their brand, UP4™ Probiotics, into Target stores nationwide. The ... is proud to add Target to its list of well-respected retailers. This list ...
Breaking Biology Technology:
Cached News: