Trio of leukemias share a single mutation

t-based recruitment, posted a questionnaire on their web site, and we had six hundred responses within just a couple of weeks."

Once candidates for the study had been identified and consent forms obtained, the researchers sent the patients kits that would enable collection of blood and mouth-swab samples by mail, said Gilliland. The patients were instructed to have their blood drawn at their local clinic, and the researchers obtained clinical records from the patients' physicians.

Gilliland concluded that the internet-based clinical protocol is "a very valuable strategy, especially for studying relatively rare genetic diseases. It has been used by epidemiologists for gathering data using questionnaires about clinical problems. But as far as I know, this is the first time that a research group has used it as a protocol for collecting blood samples to identify the cause of a disease."


Contact: Jim Keeley
Howard Hughes Medical Institute

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