Tufts Veterinary School scientists decode Cryptosporidium genome

NORTH GRAFTON, Mass., Oct. 28, 2004 - A team of scientists at Tufts University School of Veterinary Medicine has helped decode the genome sequence of Cryptosporidium hominis, an insidious parasite identified as one of the most common causes of waterborne diseases in humans and classified by the Centers for Disease Control and Prevention as a potential bioterrorist agent. The researchers' findings are reported in today's issue of the journal Nature.

Cryptosporidium hominis is a highly contagious parasite that lives in the intestines of infected humans. Since there are no effective treatments, it is a relentless public health concern.

"Sequencing the genome of Cryptosporidium will help us determine the underlying mechanisms of the organism's unusual resistance to antimicrobial agents, and enable us to develop preventive vaccines and/or pharmaceutical treatments," said Saul Tzipori, PhD, director of Tufts' Division of Infectious Diseases and a member of the multi-institutional team researching the genome.

Present in drinking and recreational water throughout the world, Cryptosporidium causes watery diarrhea that can lead to dehydration, weight loss, stomach cramps, fever, nausea, and vomiting. While healthy people usually overcome illnesses caused by the organism, it can be life threatening to malnourished children and people whose immune systems have been compromised because of cancer, AIDS, etc.

The Cryptosporidium pathogen, which can be found in the feces of both humans and animals, is difficult to work with, thereby impeding the efforts of investigators to conduct laboratory investigations and develop appropriate therapies.

Tufts researchers successfully isolated and propagated Cryptosporidium hominis in 2000, making Tufts the first research institution capable of propagating this pathogen.

In 2000, Tufts applied to the National Institutes of Health (NIH) for funding to enable a consortium o

Contact: Barbara Donato
Tufts University

Page: 1 2

Related biology news :

1. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
2. Tufts researchers are keeping track of vitamin K: Research summary
3. Friedman School of Nutrition Science and Policy at Tufts University...
4. Tufts David Walt named Howard Hughes Medical Institute Professor
5. Tufts expert examines the cardiovascular benefits of a Mediterranean-style diet
6. Tufts professor chews on the nutrition-oral health connection
7. The latest information coming from the Friedman School of Nutrition Science and Policy at Tufts University
8. Tufts nutrition scientists say it is premature to focus on nutrient supplements over diet
9. Tufts researchers shine light on firefly mysteries
10. Research notes: Policy points from the Friedman School of Nutrition Science and Policy at Tufts
11. Research news from the Friedman School of Nutrition Science and Policy at Tufts University

Post Your Comments:

(Date:6/3/2016)... , June 3, 2016 ... von Nepal hat ... Lieferung hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung ... in der Produktion und Implementierung von Identitätsmanagementlösungen. ... Ausschreibung im Januar teilgenommen, aber Decatur wurde ...
(Date:5/24/2016)... superior patient care by providing unparalleled technology to leaders of the medical imaging industry. ... recently added to the range of products distributed by Ampronix. Photo - ... ... ... ...
(Date:5/3/2016)... May 3, 2016  Neurotechnology, a provider of ... MegaMatcher Automated Biometric Identification System (ABIS) , a ... projects. MegaMatcher ABIS can process multiple complex biometric ... combination of fingerprint, face or iris biometrics. It ... and MegaMatcher Accelerator , which have ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... --  Ginkgo Bioworks , a leading organism design ... awarded as one of the World Economic Forum,s ... innovative companies. Ginkgo Bioworks is engineering biology to ... in the nutrition, health and consumer goods sectors. ... including Fortune 500 companies to design microbes for ...
(Date:6/24/2016)... SAN DIEGO , June 24, 2016 /PRNewswire/ ... that more sensitively detects cancers susceptible to PARP ... individual circulating tumor cells (CTCs). The new test ... of HRD-targeted therapeutics in multiple cancer types. ... therapies targeting DNA damage response pathways, including PARP, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Researchers at ... most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are the ... read it now. , Diagnostic biomarkers are signposts in the blood, lung fluid ...
(Date:6/23/2016)... WI (PRWEB) , ... June 23, 2016 , ... ... supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, into ... for over 35 years, is proud to add Target to its list of ...
Breaking Biology Technology:
Cached News: