U. Va. Health System to develop new approaches to treat type 1 diabetics with islet cell transplants

CHARLOTTESVILLE, Va., Nov. 15, 2004 The University of Virginia Health System has won a $1.2 million grant over five years from the National Institutes of Health to take islet cell transplantation to the next level. Earlier this year, U.Va. performed the first islet cell transplant in Virginia. The grant could increase the number of islet cell transplants performed at U.Va. in clinical trials in the coming years.

"The idea is to develop a safer, more effective protocol to perfect islet cell transplantation and move the procedure to the next level. There is a lot to do to make this procedure more effective and more applicable to people with type 1 diabetes in this country and worldwide, " said Dr. Jerry Nadler, chief of the Division of Endocrinology and Metabolism at U.Va. and principal investigator of the new NIH grant.

For people with type 1 diabetes, where the body's own immune system kills insulin-producing cells in the pancreas, this transplant can offer hope of a life without daily insulin injections. The procedure involves injecting millions of insulin-making islet cells from donated pancreases into the liver, where the cells begin manufacturing insulin again.

However, some patients become insulin dependent several months or years after a transplant. Patients are also required to take immunosuppressant drugs to prevent rejection of the islets- strong medications that can have toxic side effects.

Now, U. Va. physicians and researchers in the Diabetes and Hormone Center of Excellence and the Department of Surgery have been chosen to join a consortium of five academic medical centers, organized by the NIH under a $75 million grant, to develop and perform new protocols to improve the safety and long-term success of islet cell transplantation. U. Va. experts will be working with principal investigators at the University of Miami's Diabetes Research Institute.

"The data suggests that in three or four years about

Contact: Bob Beard
University of Virginia Health System

Page: 1 2

Related biology news :

1. Sugar and spice and everything nice: Health differences in newborn girls and boys
2. Health Physics Society
3. Johns Hopkins Bloomberg School of Public Health, Geisinger launch new environmental research group
4. Health care reimagined: Improving patient care through early health
5. Healthy coral reefs hit hard by warmer temperatures
6. Healthy reefs hit hardest by warmer temperatures
7. Kent State University and Summa Health System receive NIH grant to study prehypertension
8. Health disparities -- Genetics, society and race play an important role in access to healthcare
9. OneWorld Health selects Odyssey Research for phase 4 study in India
10. Healthy coastal wetlands would adapt to rising oceans
11. New Geisinger Health System building green Center for Health Research

Post Your Comments:

(Date:7/2/2020)... CITY, Calif. (PRWEB) , ... July 01, 2020 ... ... biotech company, presented its phase 1a findings of Neihulizumab, a biologic for the ... conference in June 2020. Led by hemato-oncologist Dr. Paul J Martin of the ...
(Date:7/1/2020)... ... 2020 , ... Catalent, a global leader in clinical supply ... facility in Minakuchi, located in the Shiga prefecture of Japan. , Operating in ... new 60,000-square-foot facility will provide customers with flexible clinical supply solutions, serving both ...
(Date:6/28/2020)... ... June 25, 2020 , ... ... for biopharmaceutical R&D, today announced that it has entered into a multi-year ... antibodies (Multiclonics®), to support their translational and clinical research strategy to discover ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... , ... July 29, 2020 , ... ... of the top radiation centers in 16 countries, has reached its 20th anniversary ... is now in routine use at top universities including University of Pennsylvania, University ...
(Date:7/18/2020)... ... July 16, 2020 , ... “We are thrilled to deliver this ... the only technology of its kind on the market and we were pleased that ... protective capacity of traditional cultured ingredients, creating a natural way to extend the shelf ...
(Date:7/10/2020)... (PRWEB) , ... July 09, ... ... biotechnology company, announced today that Massachusetts Institute of Technology (MIT) has expanded ... broader license allows PathSensors to move into the point-of-care diagnostic market, focusing ...
(Date:7/7/2020)... ... 2020 , ... Bio-IT World has announced the winners of ... University of Chicago, Massachusetts General Hospital, Mission: Cure, and the Pistoia Alliance were ... outstanding examples of how technology innovations and strategic initiatives can be powerful forces ...
Breaking Biology Technology:
Cached News: