HOME >> BIOLOGY >> NEWS
U of MN will lead national research study on causes of bone cancer in children

Logan Spector, Ph.D., a University of Minnesota Cancer Center researcher, has received a $1.7 million grant from the National Cancer Institute (NCI) to lead the largest and most comprehensive study to date on the causes of pediatric osteosarcoma.

Osteosarcoma is a cancer of the bone that usually affects the long bones of the arm or leg. It is the most common cancer of the bone in children under 20 years of age in the United States. Each year about 400 children are diagnosed with the disease.

Spector is an assistant professor of pediatrics at the University of Minnesota Medical School and Cancer Center. The University of Minnesota is a national research and treatment site for children with bone cancer. This four-year research study will include 500 children in the United States and Canada who have been diagnosed with osteosarcoma. Their parents also will be enrolled in the study.

"Previous research has shown a close correlation between the childhood growth curve and osteosarcoma," Spector says. "Children with a more rapid or sustained growth spurt may have a higher risk of osteosarcoma.

"Our research will investigate the effects of genes related to bone growth to determine if they have a role in causing this cancer." Spector says. "We think there could be a link between bone growth genes and osteosarcoma because the timing and extent of adolescent bone growth are mostly genetic. "We also will study how well the cells repair DNA damage naturally, and if the genes are impacted by diet, physical activity, family health history, and other lifestyle-related habits."

A DNA sample will be obtained from each child with osteosarcoma as well as from the parents to learn if the children inherited these bone growth genes more or less often than expected. Growth records of children with the disease will also be compared to national standards, and all participants will complete a questionnaire about their family history and lifestyle.


'"/>

Contact: Jenna Langer
lang0712@umn.edu
612-626-4784
University of Minnesota
21-May-2007


Page: 1

Related biology news :

1. Multinational research: protecting ecology means understanding people, too
2. National Ecological Observatory Network featured at ESA/SER Joint International Conference
3. American buffalo slaughter fueled by international trade
4. NCRR launches national network to connect investigators based at minority institutions
5. CRESIB coordinates an international consortium to fight malaria caused by Plasmodium vivax
6. 2 MSU professors spearhead international water project
7. International team to honor 30th anniversary of deep-sea vent discovery in Galpagos
8. 2nd International EuroFIR Congress
9. Nature surrenders flowery secrets to international team
10. Fibers are center stage at international conference
11. UT Southwestern joins national clinical trial to uncover long-term effects of West Nile virus

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/11/2020)... OLDSMAR, Fla. (PRWEB) , ... June 08, 2020 ... ... increased demand for masks and other protective measures to protect workers in the ... doctors and their dedicated staffs who valiantly risk their lives every day to ...
(Date:6/5/2020)... (PRWEB) , ... June 04, 2020 , ... “Although we ... health and well-being of our attendees, staff, and the public. We remain committed ... and safe ways to collaborate virtually,” said Julie Sutcliffe, President of WMIS. ...
(Date:5/30/2020)... ... May 29, 2020 , ... eInfochips, a ... globally, has collaborated with EchoNous Inc. to develop the cloud-based connected health KOSMOS ... heart function, which has been clinically tested versus expert measurements, yielding improved results ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... TORONTO (PRWEB) , ... July 29, 2020 , ... eSource ... and inefficiencies. This webinar will cover the history of eSource, the reasons it did ... From EMR/EHR to wearables, to site source, the industry is moving towards capturing data ...
(Date:7/18/2020)... ... ... “We are thrilled to deliver this new technology to the industry” said ... on the market and we were pleased that the IFT jury recognized that.” reFRESH™ ... creating a natural way to extend the shelf life and improve the safety of ...
(Date:7/10/2020)... ... 2020 , ... In most research using the zebrafish model, ... in zebrafish embryos, maintaining optical transparency to facilitate microscopic imaging. Over the past ... the zebrafish model to investigate the causes of leukaemia and its relationship with ...
(Date:7/1/2020)... ... 29, 2020 , ... The Interlocal Purchasing System (TIPS), a ... recently named BioFit Engineered Products an Awarded Vendor. Awarded Vendor status ... cafeteria tables, book trucks and carts at discounted pricing without the delay and ...
Breaking Biology Technology:
Cached News: