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UCLA researchers discover new method to generate human bone

and the treatment prohibitive for many.

Ting, who works frequently with children who have congenital anomalies, began his bone research eight years ago. Wu joined him three years ago, and their collaboration resulted in the recent discovery.

"I thought it was important to understand how accelerated bone growth in one situation might be applied to situations where more bone growth could accelerate healing in those patients who lacked normal or necessary bone formation," Ting said. "This discovery will provide another option for patients. Competition will make treatment options safer, less expensive and more accessible for those families who really need it."

The team of UCLA researchers, under the business name Bone Biologics, already has begun forming partnerships that may assist in the development of appropriate carriers for UCB. The Musculoskeletal Transplant Foundation, the nation's largest tissue bank, has signed a collaborative development agreement with Wu and Ting to provide customized tissue forms to support the delivery of UCB.

"We are excited by the initial work of Drs. Wu and Ting," said Bruce Stroever, president and CEO of the Musculoskeletal Transplant Foundation. "The development of new protein sources tied to an appropriate carrier that encourages new bone formation and speeds healing is work that is synergistic to the foundation's mission of advancing the science of bone, ligament, cartilage and skin transplantation. We are pleased to be working with UCLA."

Wu and Ting anticipate FDA approval and first sales of the product in the next seven to nine years. Other collaborators on this technology include Dr. Xinli Zhang and Dr. Chia Soo at UCLA, and Dr. Shunichi Kuroda at Osaka University. The new technology recently has been awarded the prestigious 2005 Hatton Award from the International Association of Dental Research.


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Contact: Melissa Abraham
mabraham@support.ucla.edu
310-206-0540
University of California - Los Angeles
21-Apr-2005


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