HOME >> BIOLOGY >> NEWS
UGA researchers discover cell-wall carbohydrate that is crucial to anthrax bacterium

Athens, Ga. -- A week after the 9/11 attacks in 2001, the letters began to arrive. Someone filled envelopes with a deadly strain of anthrax bacteria and mailed them to two U.S. senators and several offices of the news media. Five people died, and 17 others became infected.

Since that time, governmental authorities have been engaged in a race to find ways to keep citizens safe if terrorists attack again with Bacillus anthracis, the bacterium that causes anthrax. Now, researchers at the University of Georgia, collaborating with scientists at the federal Centers for Disease Control and Prevention (CDC) in Atlanta, have discovered the structure of a unique cell-wall carbohydrate in B. anthracis.

The unique nature of the carbohydrate makes the molecule an important target for evaluating its role in virulence and survival of the anthrax bacterium, the development of new diagnostic tests and perhaps even as a new vaccine additive.

Russell Carlson of the department of biochemistry and molecular biology at the University of Georgia and faculty member at UGA's Complex Carbohydrate Research Center (CCRC), was corresponding author on a paper reporting the research, which was just published in the online version of the Journal of Biological Chemistry. Other authors from the CCRC include Biswa Choudhury, Christine Leoff, Elke Saile and Elmar Kannenberg. Collaborators at CDC were Patricia Wilkins and Conrad P. Quinn.

Anthrax is a naturally occurring animal disease. This year alone there have been several large outbreaks in animals in the U.S. and Canada, so understanding the structure of important parts of B. anthracis has a wide variety of potential applications. The new UGA research is not directly about vaccine development, and much more research needs to be done before the full potential of this unique anthrax molecule is understood.

The problems facing researchers as they unravel all the molecular riddles of anthrax are
'"/>

Contact: Philip Lee Williams
phil@franklin.uga.edu
706-542-8501
University of Georgia
29-Sep-2006


Page: 1 2

Related biology news :

1. Innovative tagging technique may help researchers better protect fish stocks
2. Penn researchers discover how key protein stops inflammation
3. ASU researchers partner with UOP to make biofuel for military jets a reality
4. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
5. Penn researchers discover pathway that eliminates genetic defects in red blood cells
6. U-M researchers find family of on switches that cause prostate cancer
7. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
8. Pets could be source of multiresistant bacteria infections in humans, MU researchers investigate
9. MGH researchers confirm that bone marrow restores fertility in female mice
10. Smithsonians National Zoo researchers use electronic eggs to help save threatened species
11. U-M researchers identify gene involved in breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
(Date:4/6/2017)... April 6, 2017 Forecasts by ... Document Readers, by End-Use (Transportation & Logistics, Government & ... Gas & Fossil Generation Facility, Nuclear Power), Industrial, Retail, ... Are you looking for a definitive report ... ...
(Date:4/4/2017)... NEW YORK , April 4, 2017   ... solutions, today announced that the United States Patent and ... The patent broadly covers the linking of an iris ... the same transaction) and represents the company,s 45 th ... our latest patent is very timely given the multi-modal ...
Breaking Biology News(10 mins):
(Date:8/17/2017)... ... August 17, 2017 , ... ... personalized medicine, today announced the launch of a new breast cancer monitoring study ... goal is to evaluate the potential for early detection of recurrent breast cancer ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... a different cell type. Many treatments for specific cancers, such as breast, prostate, ... targeted treatment is androgen deprivation therapy for advanced prostate cancer. , This ...
(Date:8/16/2017)... ... 2017 , ... We are proud to announce the successful ... Dilworth, MN site. The inspection took place Monday, July 31st through Friday, August ... a routine Bioresearch Monitoring Program (BIMO) with the USFDA wherein multiple Dermatology Vasoconstriction ...
(Date:8/15/2017)... 2017 After spending the past two years building a ... collection, GeneFo now offers this platform to healthcare stakeholders (hospitals, foundations, ... adherence, and data collection vis a vis their members, under their ... launch of this offer. ... ...
Breaking Biology Technology:
Cached News: