l different frequencies, one of which resonates with, and is attenuated (absorbed) by the swim bladders of the herring (analogous to x-rays being absorbed by water in human lungs). Diachok proposes that the whales might use this phenomenon to infer the fish length, species, and size of school. (Paper 4aAO5)
--Lay-language paper at http://www.acoustics.org/press/151st/Diachok.html
---Meeting abstract at http://asa.aip.org/web2/asa/abstracts/search.jun06/asa668.html
--Also see lay-language paper on similar topic (Killer Whales and Herring: Using Sound to Get a Meal, by Lee Miller et al.) at http://www.acoustics.org/press/151st/Miller.html

3. Noninvasively Delivering Molecules to Specific Brain Regions
Presenter: Elisa Konofagou, (ek2191@columbia.edu), Columbia University
The Blood Brain Barrier (BBB) prevents pathogens in the bloodstream from entering the brain, but it also prevents the admission of potentially helpful drugs. Researchers in recent years have discovered that ultrasound can temporarily open up the BBB. Injecting microbubbles into mice and applying ultrasound transcranially (through intact skin and skull), a Columbia University group (Elisa Konofagou and James Choi, jjc2132@columbia.edu) has demonstrated that it is possible to send gadolinium, an FDA-approved contrast agent used for medical imaging, directly and noninvasively into a part of the mouse brain known as the hippocampus. These results demonstrate the very promising feasibility of using ultrasound to noninvasively deliver drugs to specific parts of the brain. (Paper 1aBB11)
--Lay-language paper at http:/
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Contact: Ben Stein
bstein@aip.org
301-209-3091
American Institute of Physics
24-May-2006

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