HOME >> BIOLOGY >> NEWS
USC-led researchers use stem cells to regenerate parts of teeth

Los Angeles, CA., Dec.20, 2006A multi-national research team headed by USC School of Dentistry researcher Songtao Shi, DDS, PhD, has successfully regenerated tooth ro ot and supporting periodontal ligaments to restore tooth function in a swine (an animal) model. The breakthrough holds significant promise for clinical application in human patients.

The study appears December 20 in the inaugural issue of PLoS ONE.

Utilizing stem cells harvested from the extracted wisdom teeth of 18- to 20-year olds, Shi and colleagues have created sufficient root and ligament structure to support a crown restoration in their mini-pig (animal) model. The resulting tooth restoration closely resembled the original tooth in function and strength.

The technique relies on stem cells harvested from the root apical papilla, which is responsible for the development of a tooth's root and periodontal ligament. Previous studies conducted by Shi and collaborator Stan Gronthos at the National Institutes of Health had utilized dental pulp stem cells. Shi found the new technique to be superior.

"The apical papilla provides better stem cells for root structure regeneration. With this technique, the strength of the tooth restoration is not quite as strong as the original tooth, but we believe it is sufficient to withstand normal wear and tear," says Shi.

He hopes to move the technique to clinical trials within the next several years, a potential boon for dental patients who are not appropriate candidates for dental implant therapy or would prefer living tissue derived from their own teeth.

"Implant patients must have sufficient bone in the jaw to support the implant. For those who don't, this therapy would be a great alternative," says Shi.

According to Shi, the not-so-distant future may be one in which not only wisdom teeth, but those baby teeth once left to the tooth fairy for a pittance, will become valuable therapeutic tools.
'"/>

Contact: Jon Weiner
323-442-2830
Public Library of Science
20-Dec-2006


Page: 1 2

Related biology news :

1. USC-led researchers use stem cells to regenerate parts of teeth
2. USC-led team of scientists recreates DNA-mending pathway in test-tube
3. Innovative tagging technique may help researchers better protect fish stocks
4. Penn researchers discover how key protein stops inflammation
5. ASU researchers partner with UOP to make biofuel for military jets a reality
6. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
7. Penn researchers discover pathway that eliminates genetic defects in red blood cells
8. U-M researchers find family of on switches that cause prostate cancer
9. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
10. Pets could be source of multiresistant bacteria infections in humans, MU researchers investigate
11. MGH researchers confirm that bone marrow restores fertility in female mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... HONG KONG , March 30, 2017 ... developed a system for three-dimensional (3D) fingerprint identification by adopting ground ... technology into a new realm of speed and accuracy for use ... applications at an affordable cost. ... ...
(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... CENTRE, N.Y. , March 27, 2017 /PRNewswire-USNewswire/ ... Healthcare Information and Management Systems Society (HIMSS) Analytics ... Outpatient EMR Adoption Model sm . In addition, ... 12% of U.S. hospitals using an electronic medical ... CHS for its high level of EMR usage ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... (PRWEB) , ... June 22, 2017 , ... ... superior results to clients throughout the biopharma and life sciences industries, continue to ... industry is seeing. Tunnell’s Kip Wolf will be speaking on “The State of ...
(Date:6/22/2017)... ... June 22, 2017 , ... Charm Sciences, Inc. is pleased to ... was determined to be appropriate as a screening test at dairies and farms for ... EZ system, and the Charm EZ Lite system. These systems are a combination incubator ...
(Date:6/20/2017)... ... June 20, 2017 , ... HorizonScan is ... which pose the most likely threat to their products at the annual IFT ... , IFT's annual food expo attracts over 20,000 attendees representing food science professionals ...
(Date:6/20/2017)... ... June 20, 2017 , ... Do More with OHAUS ... from being a trusted supplier in the weighing industry, to extending its expertise across ... essays, enzyme reactions, immunoassays, hybridizations and more, allowing for its customers to ...
Breaking Biology Technology:
Cached News: