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UT Southwestern researchers uncover gene variant that appears to predict type 2 diabetes

ally identifying people at risk for type 2 diabetes and developing drug therapies that could be used to prevent its onset.

"Dr. Abate's previous studies showed that abnormalities in the gene ENPP1 contributed to insulin resistance. Now, Dr. Abate and his associates have demonstrated that this gene's effects on insulin resistance have biological significance in that its abnormalities make it more likely that people will develop diabetes," Dr. Grundy said. "This study is particularly revealing because of the past difficulty in identifying diabetes-causing genes on the part of geneticists working in the diabetes field."


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Contact: Donna Steph Hansard
donna.hansard@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
25-Mar-2005


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