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UT Southwestern scientist elected to National Academy of Sciences' Institute of Medicine

DALLAS Oct. 24, 2005 A UT Southwestern Medical Center faculty member who specializes in gene regulation has been elected to the Institute of Medicine, a component of the prestigious National Academy of Sciences, it was announced today.

Dr. Steven McKnight, chairman of biochemistry, was one of only two Texans among the 64 new members elected in 2005 to the organization, which addresses national health issues.

He brings the total number of current UT Southwestern faculty members inducted into the institute to 17, the largest representation at one institution in Texas and surrounding states.

Members of the Institute of Medicine shape policies affecting public health and advise the federal government on issues involving medical care, research and education. Selection is based on international distinction in science, clinical medicine, public health or medical administration. Inductees are elected by incumbent members.

"This is a notable honor for one of UT Southwestern's most distinguished and accomplished faculty members," said Dr. Kern Wildenthal, president of UT Southwestern. "Dr. McKnight's research has transformed biochemistry and molecular biology, and will have profound potential effects in medical care. We are extremely pleased that his achievements have been nationally recognized by his colleagues."

Dr. McKnight's work reaches back 20 years, when he found that a gene that binds to DNA resembled genes that cause cancer. He correctly predicted that the so-called oncogenes would also bind to DNA.

More recently, he discovered a mutation in gene "switches" that causes a condition resembling schizophrenia in mice. Another project has linked mutations in genes that control the body's "clock" to several conditions, including abnormal eating and sleeping patterns and signs of depression.

"I'm very honored," Dr. McKnight said of his election. "My research on gene regulation ended up being more pertinent to medicine than one would h
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Contact: Donna Steph Hansard
donna.hansard@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
24-Oct-2005


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