UT Southwestern scientist receives NIH Director's Pioneer Award

alyze or treat a specific disease, Dr. Kodadek said.

"As a diagnostic tool, this technique is quite promising," he said. "It's also conceivable that there's a pathway to therapeutics here. It might be that the disease-specific autoantibodies identified in this way are involved directly in the disease process and could be neutralized by the peptoid. This might provide a route to blocking particular antibody or T cell reactions selectively without touching anything else."

Over the five years of the award, Dr. Kodadek and his colleagues will simultaneously test the usefulness of peptoids as a diagnostic tool in humans and as a therapy in mice.

His work is an example of translational research, which links researchers and clinicians so that discoveries in the lab lead quickly to methods of diagnosing and treating patients.

"We are delighted by this recognition of Tom Kodadek and his work," said Dr. Greg Fitz, chairman of internal medicine. "Tom has been at the forefront of technological innovation aiming to move us closer to the goal of personalized medicine on the molecular basis of disease.

"He has a unique ability to bridge the gap between patients and science to make this happen. I expect that this is the first of many such awards."

Dr. Kodadek is also director of the UT Southwestern Center for Proteomics Research, one of 10 centers funded by the National Heart, Lung and Blood Institute. The center is dedicated to developing novel technologies for proteomics the large-scale study of the structure and functions of proteins.

Dr. Kodadek received his bachelor's degree from the University of Miami. After receiving his doctorate in organic chemistry from Stanford University, he joined UT Austin as a faculty member. He joined the UT Southwestern faculty in 1998.

Dr. Steven McKnight, chairman of biochemistry at UT Southwestern, received a Pioneer Award in 2004 and was the first recipient fr

Contact: Aline McKenzie
UT Southwestern Medical Center

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