UW-Madison work on stem cells, cardiac health to be presented at ACS

MADISON - Several University of Wisconsin-Madison engineers will present findings at the American Chemical Society's national meeting, held through Thursday, Sept. 14, in San Francisco. Among them, two presentations will highlight research that could benefit cardiac health and stem cell research.

Clearing clogged arteries with DNA-coated stents

CONTACT: David M. Lynn, (608) 262-1086, dlynn@engr.wisc.edu

New materials hold promise for treating cardiovascular diseases with gene-based therapy using intravascular stents, small tubes of metal mesh that are commonly inserted into arteries to keep them open after angioplasty. Led by chemical and biological engineer David M. Lynn, a team has developed methods to coat stents with films of nanostructured layers of DNA and cationic polymers. The polymers degrade and DNA is released into the surrounding cells.

This approach is similar to current stents coated with small-molecule drugs. "While current stent coatings work well for releasing traditional drugs, they were not designed to release nucleic acid-based drugs," says Lynn.

One important application of localized gene-based therapy is the prevention of restenosis, a common problem with metal stents, in which smooth muscle tissue grows over and around the stent, which can re-clog the artery.

Lynn will present his findings at 8:50 a.m. on Thursday, Sept. 14, in the B1 salon of the San Francisco Marriott. He will be available for questions after the session.

Improving stem cell production

CONTACT: Juan de Pablo, (608) 262-7727, depablo@engr.wisc.edu

In a typical culture, human embryonic stem cells (hESC) grow in colonies that are mixed in size and shape. These colonies often spontaneously differentiate, making it time- and labor-intensive to maintain undifferentiated cells.


Contact: David M. Lynn
University of Wisconsin-Madison

Page: 1 2

Related biology news :

1. UW-Madison researchers find new way to sweeten key drugs
2. UW-Madison research part of international mercury conference
3. UW-Madison engineers squeeze secrets from proteins
4. UW-Madison small-scale research receives big boost
5. $3.4 million directed to key UW-Madison MS study
6. UW-Madison scientists zero in on drugs sweet spots
7. UW-Madison gains two new stem cell programs
8. Water research initiatives at UW-Madison
9. New biochip helps study living cells, may speed drug development
10. Cloned mice created from fully differentiated cells, a milestone in cloning research
11. Drug dials down the energy within cells, UM researchers find

Post Your Comments:

(Date:4/30/2020)... ... ... Pebble Labs USA Inc. , a biotechnology company developing solutions that ... of improving global food security, announced today that they have been selected as one ... Ag-Tech ' virtual event, a global initiative to drive innovation in feeding future generations. ...
(Date:4/30/2020)... ... April 29, 2020 , ... At the start of 2020 ... solutions for a wide range of industries including pharmaceutical and biopharmaceutical manufacturing, healthcare, ... the new decade, it was clear to company leadership that they would have ...
(Date:4/26/2020)... ... 2020 , ... SECO , a leading company in ... by Fondo Italiano d’Investimento SGR, today announced a partnership with IBD, an innovative ... new non-invasive pulmonary ventilator created in response to the current health emergency of ...
Breaking Biology News(10 mins):
(Date:4/7/2020)... ... 2020 , ... Gateway Genomics , leading developer of direct-to-consumer genetic tests ... DNA Tests sold in March, just months after attaining the 150,000-test landmark in ... a mom could order her kit online, collect a DNA sample from her home, ...
(Date:4/1/2020)... , ... March 30, 2020 , ... ... its latest product, ArmourGuard® RTU, an EPA-approved spray-on antimicrobial solution. As a first-of-its-kind ... solution that provides continual antimicrobial activity against microorganisms for up to 90 days. ...
(Date:4/1/2020)... ... March 31, 2020 , ... Dutch ... its revolutionary NEXTGENPCR endpoint thermocycler and consumables that decreases PCR amplification time ... per run, and standard, affordable laboratory equipment, a qualitative protocol was generated ...
(Date:4/1/2020)... ... March 31, 2020 , ... Bedoukian ... signing of a Joint Development Agreement that builds on each company’s expertise in ... global leader in the supply of high-quality insect pheromones as well as flavors ...
Breaking Biology Technology:
Cached News: