HOME >> BIOLOGY >> NEWS
Unicellular microRNA discovery

In the May 15th issue of Genes & Development, an international collaboration of researchers, led by Dr. Yijun Qi (National Institute of Biological Sciences, China), report on their discovery of microRNAs in the unicellular green alga, Chlamydomonas reinhardtii. This is the first finding of microRNAs in a unicellular organism.

"The finding changes the dogma that miRNAs only exist in multicellular organisms, and adds an important piece into the blooming small RNA world. A pressing question we have now is what these miRNAs are exactly doing in the green alga. I hope we will know the answers soon," says Dr. Qi.

MicroRNAs (miRNAs) are a class of conserved, approximately 21-nucleotide long RNAs that regulate the expression of genes by either cleaving complementary mRNA targets or repressing their translation. MiRNAs have been identified in both plants and animals, acting as key regulators of multicellular development.

Dr. Qi and colleagues now extend the range of miRNAs into unicellular organisms, with their discovery of a large number of miRNAs in green algae. The researchers showed that unicellular miRNAs share functional characteristics with plants miRNAs, in so far as they can direct the cleavage of target mRNAs in vitro and in vivo. Furthermore, they found that miRNA expression patterns changed during gamete differentiation, suggesting a possible role in regulating sexual reproduction.

The discovery of miRNAs in a unicellular organism has evolutionary implications as well. While the existence of miRNAs in unicellular and multicellular organisms suggests that the miRNA pathway arose before these lineages split, the lack of universally conserved miRNA genes in algae, plants and animals suggests that they may have evolved independently.


'"/>

Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
29-Apr-2007


Page: 1

Related biology news :

1. Penn researchers discover how microRNAs control protein synthesis
2. Mechanism of microRNAs deciphered
3. Xie Lab demonstrates the role of microRNA pathway
4. Pair of microRNA molecules controls major oncogene in most common leukemia
5. microRNA function in neurogenesis
6. Penn researchers find role for microRNAs in angiogenesis
7. Activation of microRNA inhibits cancer gene in human cancer cells
8. Single microRNA causes cancer in transgenic mouse
9. microRNA-mediated metabolism
10. Role of microRNA identified in thyroid cancer
11. Twin molecular scissors link creation of microRNAs with gene-silencing

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... , June 15, 2017  IBM (NYSE: IBM ) ... international tech event dedicated to developing collaboration between startups and ... on June 15-17. During the event, nine startups will showcase ... value in various industries. France ... the international market, with a 30 percent increase in the ...
(Date:5/16/2017)... , May 16, 2017  Veratad Technologies, LLC ( ... online age and identity verification solutions, announced today they ... Conference 2017, May 15 thru May 17, 2017, in ... and International Trade Center. Identity impacts ... and in today,s quickly evolving digital world, defining identity ...
(Date:5/6/2017)... RAM Group , Singaporean based ... in biometric authentication based on a novel  ... to perform biometric authentication. These new sensors are based on ... Ram Group and its partners. This sensor will have ... and security. Ram Group is a next generation ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Kapstone Medical is proud ... successes helping medical technology companies and inventors develop and safeguard their latest innovations. ... engineering firm with a portfolio of clients in the United States and around the ...
(Date:8/15/2017)... ... August 15, 2017 , ... Pittcon is pleased to ... and scientific instruments. This year’s symposium, organized by the Pittcon 2018 program chair, ... Bioanalytical Applications.” This dynamic presentation will discuss novel ionization processes, high throughput IMS-MS ...
(Date:8/15/2017)... ... August 15, 2017 , ... Kenall, a leader in sealed ... stay tightly sealed and perform efficiently for years. The downlights are ideal for ... aren't enough, such as: hospitals; behavioral health facilities; cleanrooms; containment areas; food and ...
(Date:8/15/2017)... ... August 15, 2017 , ... Coffea ... various biotic and abiotic factors. During this educational webinar, participants will learn about ... well as gain a better understanding of how genomics is important for coffee ...
Breaking Biology Technology:
Cached News: