HOME >> BIOLOGY >> NEWS
Unique genetic profile helps over-45s conceive naturally

Copenhagen, Denmark: Women who have a special genetic profile can conceive spontaneously after the age of 45 years, a scientist said at the 21st annual conference of the European Society of Human Reproduction and Embryology today (Tuesday 21 June 2005). Dr. Neri Laufer, from the Haddassah University Hospital, Jerusalem, Israel, told the conference that his team's work to identify a specific gene expression profile linked to later fertility would help understanding of the ageing process, as well as enabling the development of better treatments for infertility in older patients.

Dr. Laufer and colleagues studied a large group of 250women over 45 who conceived spontaneously. Women are generally not fertile after this age due to ageing of the ovaries, so the scientists thought that there might be some special factor that was allowing these women to conceive. "Mostly they had had a large number of children and also a low miscarriage rate", he said "and these two factors indicated to us that they had a natural ability to escape the ageing process of the ovaries. We decided to see if we could find any differences in gene expression between 8 such women and another 6 women of the same age group who had finished their families at the age of 30."

Using gene chip technology, the scientists found that blood samples from the 8 women had a unique pattern of gene expression that did not exist in the control group. The two main groups of genes expressed in these women were involved in apoptosis (cell death) and in DNA repair mechanisms. "These women appear to differ from the normal population due to a unique genetic predisposition that protects them from the DNA damage and cellular ageing that helps age the ovary", said Dr. Laufer. "What we do not yet know is whether this reproductive success is linked with potential longevity." The women were all Ashkenazi Jews but Dr. Laufer's team does not believe that the gene profile is unique to this group.
'"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
20-Jun-2005


Page: 1 2

Related biology news :

1. Unique tomatoes tops in disease-fighting antioxidants
2. Unique estrogen receptor linked to metastatic breast cancer
3. Unique imaging uncovers the invisible world where surfaces meet
4. Unique gene regulation gives chilly bugs survival advantage at bottom of the world
5. Unique Huntingtons study moves forward
6. Unique dual target specificity of kinase inhibitor key for success against cancer
7. Unique soybean lines hold promise for producing allergy-free soybeans
8. Uniquely human component of language found in gregarious birds
9. Unique equine cataract surgery offered on routine basis
10. Unique interplay between tumor and blood vessel cells promotes angiogenesis and tumor growth
11. Unique library of plant genes germinates, takes root at UNC

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... ... July 01, 2020 , ... Catalent, a global ... of Teva-Takeda Pharmaceuticals’ packaging facility in Minakuchi, located in the Shiga prefecture of ... located in Kakegawa, the new 60,000-square-foot facility will provide customers with flexible clinical ...
(Date:6/25/2020)... ... June 24, 2020 , ... eClinical Solutions ... data services that accelerate drug development, is collaborating with Karyopharm Therapeutics (Nasdaq: ... hospitalized patients with severe COVID-19. This is the first study of an XPO1 ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... pleased to announce the next event in a series of TOPIQ webinars, which ... TOPIQ series of webinars was developed in response to social distancing measures that ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... MIAMI (PRWEB) , ... July 29, 2020 , ... ... nearly 200 of the top radiation centers in 16 countries, has reached its ... years, SDX® is now in routine use at top universities including University of ...
(Date:7/18/2020)... ... July 16, 2020 , ... ... in the early detection and prevention of high-burden diseases, and Centric Consulting, a ... and healthcare organizations to utilize existing data in order to identify and prioritize ...
(Date:7/10/2020)... ... July 09, 2020 , ... Sentien Biotechnologies, Inc., a ... of Allen R. Nissenson, M.D., F.A.C.P., as its Chief Medical Officer. Dr. ... lead product, SBI-101. Dr. Nissenson serves as an Emeritus Professor of Medicine ...
(Date:7/1/2020)... ... June 30, 2020 , ... ... that the launch of a new clinical diagnostics immuno-oncology service, TissueInsight ... microenvironment (TME). , “Flagship’s TissueInsight is a service that aids pathologists, oncologists, ...
Breaking Biology Technology:
Cached News: