HOME >> BIOLOGY >> NEWS
University of California, San Diego-led team discovers how we detect sour taste

A team headed by biologists from the University of California, San Diego has discovered the cells and the protein that enable us to detect sour, one of the five basic tastes. The scientists, who included researchers from the National Institute of Dental and Craniofacial Research, suggest that this protein is also the long-sought sensor of acidity in the cerebrospinal fluid.

The study, featured on the cover of the August 24 issue of the journal Nature, reports that each of the five basic tastes is detected by distinct taste receptors--proteins that detect taste molecules--in distinct cells. The team previously discovered the sweet, bitter and umami (savory) receptors and showed that they are found in separate cells, but some researchers have argued that sour and salty tastes, which depend on the detection of ions, would not be wired in the same way.

"Our results show that each of the five basic taste qualities is exquisitely segregated into different taste cells" explained Charles Zuker, a professor of biology at UCSD and a Howard Hughes Medical Institute Investigator, who headed the study. "Taken together, our work has also shown that all taste qualities are found in all areas of the tongue, in contrast with the popular view that different tastes map to different areas of the tongue."

To determine if the taste cells and receptors for sour were separate from the receptors for the other basic tastes, the researchers tested mice in which they had genetically ablated the cells containing the sour taste receptors. The mice could not taste sour, but had completely normal sweet, bitter, umami and salty tastes. Therefore, although the salt taste receptor has not yet been discovered, it and the four identified receptors must each be segregated into distinct taste cells.

In addition to being found in the taste buds, the researchers discovered that the sour protein receptor, PKD2L1, is also found along the entire length of the spin
'"/>

Contact: Sherry Seethaler
sseethaler@ucsd.edu
858-534-4656
University of California - San Diego
23-Aug-2006


Page: 1 2 3

Related biology news :

1. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
4. $9M grant awarded to University of Cincinnati for bipolar disorder research
5. University of Leeds strengthens China links in membrane and neurobiology
6. University of Colorado licenses two influenza virus detection discoveries to Quidel Corp.
7. Manchester University helps with pharaoh DNA analysis
8. University of Cincinnati receives $1.7M to research molecular treatment of brain injury
9. University of Arizona launches major scientific research initiative at Biosphere 2
10. Link between obesity and enlarged heart discovered by University of Arizona researchers
11. Bee researcher at Arizona State University is 1 of 20 new Pew Scholars in the biomedical sciences

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2020)... SCOTTSDALE, Ariz. (PRWEB) , ... May 20, 2020 , ... ... justice, and remove danger for all of us. The positions of these men and ... as from the defense for not following rules precisely. Officers have always had to ...
(Date:5/15/2020)... FREDERICK, Md. (PRWEB) , ... May 15, 2020 , ... ... a boutique intellectual property law firm based in Frederick, Maryland and Tysons Corner, Virginia, ... the field of biotechnology and a another in the field of chemistry. The firm ...
(Date:5/14/2020)... ... May 13, 2020 , ... DuPont ... latest enzyme for the lactose-free dairy market. This unique product allows for process ... dairy products at competitive costs across North America. , Among the numerous benefits ...
Breaking Biology News(10 mins):
(Date:7/7/2020)... ... July 06, 2020 , ... Bio-IT World has announced ... Bristol-Myers Squibb, the University of Chicago, Massachusetts General Hospital, Mission: Cure, and the ... awards program, highlighting outstanding examples of how technology innovations and strategic initiatives can ...
(Date:6/28/2020)... (PRWEB) , ... June 25, 2020 , ... The Indoor ... launch of Safe Space™ for businesses of all types to ensure cleanliness, distancing and ... , A Safe Space™ enabled business will provide a health performance index ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... unique lab-made bioresearch materials, today announced the availability of the Delta-G-VSV Pseudotyping System ... University of Tennessee, enables studies of SARS-CoV-2 viral entry and COVID-19 vaccine effectiveness ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... today announced that it has filed an Investigational New Drug application (IND) with ... trial of its lead drug candidate NBTX-001 in patients with panic disorder (PD). ...
Breaking Biology Technology:
Cached News: