University of Chicago study overturns conventional theory in...( d a most striking result one that is t...)

d a most striking result, one that is totally unexpected," said geneticist James Crow, professor emeritus of genetics and zoology at the University of Wisconsin-Madison. "If this result is indeed confirmed it would cast doubt on use of this ratio [Ka/Ks] as an indicator of selection."

Sudhir Kumar, an associate professor of molecular evolution at Arizona State University, agreed. "It goes against strict theory, but evolutionary biologists know that nothing's clean cut. There's always distortion because we're looking at longtime history.

"The novelty of this work is that he [Lahn] used a large amount of data," Kumar said. "It's a perfect example of the power of the genome project."

"I hope that further work will provide an explanation of what now is a major puzzle," Crow added.

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Contact: Catherine Gianaro
catherine.gianaro@uchospitals.edu
773-702-6241
University of Chicago Medical Center
7-Jun-2005

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