HOME >> BIOLOGY >> NEWS
University of Washington researchers play leading role in major study of human genome function

Scientists at the University of Washington and other members of an international consortium have completed a multi-year research effort that dramatically boosts understanding of how the human genome functions. While previous studies of the human genome have focused mainly on genes, this study provides insight into the non-gene sequences making up the vast majority of the genome. Buried in non-gene sequences are so-called "regulatory elements" that contain instructions for switching genes on or off, and for controlling how DNA is packaged and replicated within a human cell. Scientists believe these DNA sequences may play a very important role in some diseases, such as prostate or colon cancer.

The UW was a leading institution among dozens that participated in the Encyclopedia of DNA Elements (ENCODE) consortium, supported by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health. The consortium's initial results are being published in the June 14 issue of the journal Nature, and in companion articles in the June issue of the journal Genome Research.

Launched in September 2003, the consortium began a four-year pilot project to identify the function of all DNA sequences in a small section of the human genome. Though the pilot study only examined about 1 percent of the genome, scientists hope the work will build our understanding of the 98 percent of the genome that is made up of non-gene sections of DNA. The consortium also set out to create methods for easily building up the ENCODE project to encompass the entire human genome.

The UW is one of eight major data-producing centers in the consortium, along with Yale University, Stanford University, Affymetrix Inc., the University of Virginia, the University of California San Diego, the Wellcome Trust Sanger Centre in Cambridge, UK, and the NHGRI. UW researchers also led a computational analysis project that integrated data from multiple consortium mem
'"/>

Contact: Justin Reedy
jreedy@u.washington.edu
206-685-0382
University of Washington
13-Jun-2007


Page: 1 2 3

Related biology news :

1. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
4. $9M grant awarded to University of Cincinnati for bipolar disorder research
5. University of Leeds strengthens China links in membrane and neurobiology
6. University of Colorado licenses two influenza virus detection discoveries to Quidel Corp.
7. Manchester University helps with pharaoh DNA analysis
8. University of Cincinnati receives $1.7M to research molecular treatment of brain injury
9. University of Arizona launches major scientific research initiative at Biosphere 2
10. Link between obesity and enlarged heart discovered by University of Arizona researchers
11. Bee researcher at Arizona State University is 1 of 20 new Pew Scholars in the biomedical sciences

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/6/2017)... 2017 Forecasts by Product Type ... by End-Use (Transportation & Logistics, Government & Public Sector, ... Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation ... Are you looking for a definitive report on the ... ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
Breaking Biology News(10 mins):
(Date:5/22/2017)... , ... May 22, 2017 , ... ... with other leaders of the Maryland Biohealth community in developing and issuing recommendations ... Top 3 U.S. BioHealth Innovation Hub by 2023. , The ...
(Date:5/21/2017)... (PRWEB) , ... May 20, 2017 , ... ... that helps avoid the lengthy trial and error process by finding the right ... It can also strengthen the doctor-patient relationship through a personalized approach to treatment. ...
(Date:5/18/2017)... ... May 18, 2017 , ... ... April 28, 2017 at the Prince Of Wales Private Hospital. The procedure was ... level C6-C7. The patient failed conservative treatments prior to undergoing surgery. , The ...
(Date:5/18/2017)... ... 17, 2017 , ... NDA Partners Chairman Carl Peck, MD , announced ... Laboratories and President of Pharmaceutical Development Business Unit of Cardinal Health, has joined the ... Health, he was former Chief Operating Officer at Anaborex, Senior VP and General Manager ...
Breaking Biology Technology:
Cached News: