HOME >> BIOLOGY >> NEWS
University of Washington researchers play leading role in major study of human genome function

ce. Together, they created new computational techniques and used powerful computers to unravel the locations of gene-controlling sequences, and to pull together data generated by other ENCODE centers to gain a more complete picture of how the genome was working.

In the beginning we only had the vaguest idea how the various functional data sets might fit together, said Noble. Because of that, the researchers had to build their computational tools from scratch, which required several years of work. The group used the Internet to help rapidly disseminate and review complex computational analyses with researchers around the world.

Even though the ENCODE consortium studied only 1 percent of the human genome, Stamatoyannopoulos believes their research will be useful for understanding the entire genome.

The progress of the past four years has been breathtaking, as we have moved from being able to analyze only a few thousand DNA base pairs at a time, up to 1 perecnt of the genome, or 30 million bases, he said. Now, with new technologies in hand, the entire genome is within reach. Expanding the ENCODE project to the entire genome will have a major impact on our understanding of the genetic basis of common diseases, where defects in gene-controlling sequences likely play a key role.

Non-gene elements of the human genome have been relatively understudied in the past, but recent research has shown that non-gene DNA defects play a critical role in many common diseases, like prostate and colon cancer, inflammatory bowel disease, arthritis, and diabetes. By having a complete map of functional DNA within the genome, biomedical scientists will be able to track down the causes of these diseases far more rapidly than before, and will be better equipped to treat or prevent them.


'"/>

Contact: Justin Reedy
jreedy@u.washington.edu
206-685-0382
University of Washington
13-Jun-2007


Page: 1 2 3

Related biology news :

1. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Biologists at Tufts University discover 1 reason why chromosomes break, often leading to cancer
4. $9M grant awarded to University of Cincinnati for bipolar disorder research
5. University of Leeds strengthens China links in membrane and neurobiology
6. University of Colorado licenses two influenza virus detection discoveries to Quidel Corp.
7. Manchester University helps with pharaoh DNA analysis
8. University of Cincinnati receives $1.7M to research molecular treatment of brain injury
9. University of Arizona launches major scientific research initiative at Biosphere 2
10. Link between obesity and enlarged heart discovered by University of Arizona researchers
11. Bee researcher at Arizona State University is 1 of 20 new Pew Scholars in the biomedical sciences

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: