HOME >> BIOLOGY >> NEWS
Unraveling where chimp and human brains diverge

many of the genes that play a central role in cerebral cortex networks in humans, but not in the chimpanzee, also show significant changes at the DNA level.

"When we see alterations in a gene network that correspond to functional changes in the genome, it implies that these differences are very meaningful," said Oldham. "This finding supports the theory that variations in the DNA sequence contributed to human evolution."

Relying on a new analytical approach developed by corresponding author Steve Horvath, UCLA associate professor of human genetics and biostatistics, the UCLA team used data from DNA microarrays vast collections of tiny DNA spots -- to map the activity of virtually every gene in the genome simultaneously. By comparing gene activity in different areas of the brain, the team identified gene networks that correlated to specific brain regions. Then they compared the strength of these correlations between humans and chimps.

Many of the human-specific gene networks identified by the scientists related to learning, brain cell activity and energy metabolism.

"If you view the brain as the body's engine, our findings suggest that the human brain fires like a 12-cylinder engine, while the chimp brain works more like a 6-cylinder engine," explained Geschwind. "It's possible that our genes adapted to allow our brains to increase in size, operate at different speeds, metabolize energy faster and enhance connections between brain cells across different brain regions."

Future UCLA studies will focus on linking the expression of evolutionary genes to specific regions of the brain, such as those that regulate language, speech and other uniquely human abilities.


'"/>

Contact: Elaine Schmidt
eschmidt@mednet.ucla.edu
310-794-2272
University of California - Los Angeles
13-Nov-2006


Page: 1 2

Related biology news :

1. Unraveling the physics of DNAs double helix
2. Unraveling Alzheimers: Clues may be found visualizing plaques in human brain, mad cowtype diseases
3. Unraveling the viral mechanism
4. Unraveling a stomach cancer puzzle
5. High-intensity ultrasound may launch attack on cancer, wherever it lurks
6. Waters off Washington state only second place in world where glass sponge reefs found
7. Fruit fly gene from out of nowhere is discovered
8. Where did we come from, and how did we get to where we live today?
9. Why do oysters choose to live where they could be eaten?
10. Plant studies reveal how, where seeds store iron
11. Unique imaging uncovers the invisible world where surfaces meet

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2017)... -- Socionext Inc., a global expert in SoC-based imaging and computing solutions, ... which features the company,s hybrid codec technology. A demonstration utilizing TeraFaces ... will be showcased during the upcoming Medtec Japan at Tokyo Big ... Las Vegas Convention Center April 24-27. ... Click here for an image of ...
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... ... has teamed up with NASA to showcase the future of deep space exploration ... System (SLS) rocket and Orion spacecraft and includes a guest appearance by former ...
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... ... headlines and drive high-level conversations among healthcare industry stakeholders, the discussion surrounding the ... – taking place May 15-18, 2017 in Los Angeles, Calif. Hosted by the ...
(Date:4/25/2017)... Providence -based biotechnology ... technology to an undisclosed global pharmaceutical company, for ... Tregitopes, pronounced T·rej·itopes, are a set of peptides ... Annie De Groot and EpiVax CIO ... autoimmune disease therapy, Tregitopes are capable of engaging regulatory ...
(Date:4/24/2017)...  Dante Labs announced today the offer of whole genome ... While American individuals have been able to access WGS at ... WGS below EUR 1,000. The sequencing includes bioinformatics ... to make informed decisions about disease monitoring, prevention, nutrition, exercise, ... ...
Breaking Biology Technology:
Cached News: