HOME >> BIOLOGY >> NEWS
Vaccine hope for malaria

One person dies of it every 30 seconds, it rivals HIV and tuberculosis as the worlds most deadly infection and the vast majority of its victims are under five years old. Now, just over 100 years since Britains Sir Ronald Ross was awarded the Nobel Prize for finally proving that malaria is transmitted by mosquitoes, researchers at The University of Nottingham believe they have made a significant breakthrough in the search for an effective vaccine.

Malaria infects around 400 million people every year and kills between one and three million, mostly children.

Dr Richard Pleass, from the Institute of Genetics, said: Our results are very, very significant. We have made the best possible animal model you can get in the absence of working on humans or higher primates, as well as developing a novel therapeutic entity.

Using blood from a group of people with natural immunity to the disease, a team from the School of Biology refined and strengthened the antibodies using a new animal testing system which, for the first time, mimics in mice the way malaria infects humans. When injected into mice, these antibodies protected them against the disease.

The World Health Organisation (WHO) says malaria is a public health problem in more than 90 countries and describes it as by far the world's most important tropical parasitic disease. It kills more people than any other communicable disease except tuberculosis and more than 90 per cent of all malaria cases are in sub-Saharan Africa. According to WHO, the dream of the global eradication of malaria is beginning to fade with the growing number of cases, rapid spread of drug resistance in people and increasing insecticide resistance in mosquitoes.

Until now there has been no reliable animal model for human malaria. Mice do not get sick when infected with the blood-borne parasite that causes malaria in people. And the immune system of mice shows a different response to humans when it c
'"/>

Contact: Richard Pleass
44-011-582-30383
University of Nottingham
23-May-2007


Page: 1 2

Related biology news :

1. Vaccine trials inject hope into koalas future
2. Vaccine prevents prion disease in mice
3. Vaccine hope for sufferers of potentially fatal stomach bug
4. Vaccine to cope with viral diversity in HIV
5. PATH Malaria Vaccine Initiative announces partnership to develop novel malaria vaccine
6. U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
7. Vaccine-producing plant-factories
8. HPV Vaccine: Whats next
9. Vaccine shown effective against chancroid
10. Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
11. Vaccine provides 100 percent protection against avian flu virus in animal study

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2020)... JUPITER, Fla. (PRWEB) , ... June 25, 2020 , ... ... will focus on innovations in accelerated Point of Care Testing solutions (POCT). Check local ... labs. Samples are collected at medical offices and are shipped to labs throughout the ...
(Date:6/23/2020)... ... June 23, 2020 , ... Rigaku Corporation , a ... in a series of TOPIQ webinars, which will cover the Transferable Aspherical Atom ... in response to social distancing measures that resulted in postponements and cancelations of ...
(Date:6/13/2020)... ... June 11, 2020 , ... Bode ... expansion of its forensic genealogy team. Bode’s Forensic Genealogy Service (FGS) ... genealogy and DNA analysis methods. The team has added experienced genealogists, each having ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... FRANCISCO (PRWEB) , ... July ... ... provider of cloud-based software for the life sciences industry, today announced the ... presentation platform designed specifically for Medical Science Liaisons (MSLs) and other field ...
(Date:7/18/2020)... DAYTON, Ohio (PRWEB) , ... July 16, 2020 ... ... clinical data solutions to aid in the early detection and prevention of high-burden ... partnership to enable US-based hospitals and healthcare organizations to utilize existing data in ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... is commonly used to suppress pigment formation in zebrafish embryos, maintaining optical transparency ... led by Dr MA has been using the zebrafish model to investigate the ...
(Date:7/1/2020)... ... June 29, 2020 , ... ... date growth of 40% in 2020, despite many obstacles created as a result ... to increase revenue for its partnered medical practices and medical manufacturers by expanding ...
Breaking Biology Technology:
Cached News: