HOME >> BIOLOGY >> NEWS
Vaccine shown effective against chancroid

binding hemoglobin and, hence, obtaining the heme it needs to survive, the authors said.

In skin biopsies of the immunized animals, the researchers found no viable chancroid bacteria.

An HIV vaccine has been elusive in part because the virus constantly varies its surface molecules, making it an ever-changing target. But H. ducreyi, unlike other sexually transmitted bacteria, doesn't have such a protective mechanism.

The current study and other studies suggest that developing a chancroid vaccine would be a relatively simple task, Elkins said.

Commercial sex workers infected with chancroid form a "reservoir" of infection, Elkins said. A vaccine strategy of vaccinating female sex workers against chancroid could shut down the cycle of infection, eliminating the disease of not only sex workers but their sexual partners.

And evidence suggests that eliminating chancroid throughout Africa could help reduce the transmission of HIV.

"Diverting but a fraction of the effort on HIV potentially could rapidly lead to a chancroid vaccine. I believe it is imperative that international and U.S. agencies address this opportunity in a timely manner," Elkins said.

In addition to Afonina and Elkins, other UNC authors are postdoctoral research associate Dr. Isabelle Leduc and postdoctoral trainee Dr. Igor V Nepliouev, both of the Center for Infectious Diseases; Dr. Marcia Hobbs, research associate professor in the departments of medicine and microbiology and immunology; and Chrystina Jeter, former undergraduate research assistant in Elkin's lab.

Authors from N.C. State University's College of Veterinary Medicine are Patty Routh, research technician; Dr. Glen Almond, professor of population health and pathobiology; and Dr. Paul E. Orndorff, professor of population health and pathobiology and microbiology and immunology. Elkins said that further development of the vaccine studied is needed, including perfecting ways to purify large amounts of
'"/>

Contact: Leslie H. Lang
llang@med.unc.edu
919-843-9687
University of North Carolina School of Medicine
5-May-2006


Page: 1 2 3

Related biology news :

1. Vaccine trials inject hope into koalas future
2. Vaccine hope for malaria
3. Vaccine prevents prion disease in mice
4. Vaccine hope for sufferers of potentially fatal stomach bug
5. Vaccine to cope with viral diversity in HIV
6. PATH Malaria Vaccine Initiative announces partnership to develop novel malaria vaccine
7. U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
8. Vaccine-producing plant-factories
9. HPV Vaccine: Whats next
10. Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
11. Vaccine provides 100 percent protection against avian flu virus in animal study

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Vaccine shown effective against chancroid

(Date:4/1/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... mobile commerce market, announces the second shipment of a ... early access pre-order customers. Feedback from ... including Walmart, Target, AT&T, Dunkin, Donuts, Stop & Shop ... all outlets and very easy to use. Several users ...
(Date:3/26/2015)... , March 26, 2015 The ... social, recreation and athletic club, today announced it has ... allow freedom of movement for members and staff, while ... a comprehensive process, we selected FST,s IMID Access system ... convenience for our members and staff, in addition to ...
(Date:3/23/2015)... BOSTON, Mass , March 23, 2015 SoundView ... shipment of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView ... world user feedback on their experience with the Wocket in ... experience at CVS, Whole Foods and other retailers, making both ... Kris Tuttle also says, "If the company meets ...
Breaking Biology News(10 mins):NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Granite Club First Private Club in North America to Implement FST Biometrics Secure Access Solution, as Part of Multi-million Dollar Expansion 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4
(Date:4/20/2015)... , April 20, 2015 PointCross Life Sciences ... to provide an integrated Big Data and globally accessible ... collected in the context of clinical trials and nonclinical ... or multi-targeted drug candidates, stratified patient selection and ... free survival. Highlighting the timing of ...
(Date:4/20/2015)... April 20, 2015 Sinovac Biotech Ltd. (Nasdaq: ... today announced its unaudited financial results for the fourth ... Fourth Quarter 2014 Financial Highlights(Compared to the fourth ... million, a decrease of 11.4% from $22.9 million in ... stockpiling of H5N1 pandemic influenza vaccine of $0.1 million ...
(Date:4/17/2015)... ALTO, Calif. , April 17, 2015 ... has received a SBIR grant from the ... the National Institutes of Health (NIH). The ... research efforts in the development of breakthrough ... genomes using specially fabricated substrates. Centrillion has ...
(Date:4/17/2015)...  US-Australian drug discovery company, Novogen, today announced ... with the Feinstein Institute for Medical Research (,Feinstein ... to collaborate with the objective of developing effective ... brings together the drug discovery expertise of Novogen ... Feinstein Institute in neurosciences and oncology. ...
Breaking Biology Technology:PointCross Life Sciences and InterpretOmics partner for Clinical and Genomic Biomarker Management for Drug Development 2Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 2Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 3Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 4Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 5Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 6Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 7Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 8Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 9Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 10Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 11Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 12Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 13Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 14Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 15Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 16Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 17Sinovac Reports Unaudited Fourth Quarter and Full Year 2014 Financial Results 18Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 2Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 3Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 4Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 5Novogen and Feinstein Institute Join Forces to Find Effective Treatments for Brain Cancer 6
Cached News: