HOME >> BIOLOGY >> NEWS
Viral marker of human migration suspect

A benign virus previously used as a marker in tracing human migration may be unreliable, according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought.

"The most genetically divergent human populations are in Africa," said Laura Shackelton, a postdoctoral researcher at Penn State's Center for Infectious Disease Dynamics. "But, in the case of this virus, strains from European communities appear to be the most divergent."

The human polyomavirus, or JCV, is a small double-stranded DNA virus that is thought to be primarily transmitted from parents to their children. Infection is usually asymptomatic unless a person has a weak immune system, in which case the virus can cause neurological disease.

There are more than 14 subtypes of the virus, each primarily associated with different human populations such as African, Japanese, South Asian, and European. Population geneticists have assumed that the virus has been with humans since their emergence from Africa.

"Because of this presumed codivergence with human populations, JCV has been widely used as a genetic marker for human evolution and migration," explained Shackelton, whose findings appear this month (October) in the Journal of Virology.

The researchers note that while previous studies of genetic variation have observed some differences between the distribution of JCV and human populations, the extent of the differences in their evolutionary histories has never been fully tested.

Shackelton and her colleagues analyzed 333 genetic sequences of the virus and reconstructed their evolutionary history. They then compared this history to the reconstructed history of human populations, based on mitochondrial DNA.

"If the virus had been with humans since we were a single population, and we have almost strictly transmitted it to our children, you may expect that as populatio
'"/>

Contact: Amitabh Avasthi
axa47@psu.edu
814-865-9481
Penn State
24-Oct-2006


Page: 1 2

Related biology news :

1. Viral enzyme recruited in fight against ear infection
2. Viral protein is an effective preventative against infection
3. Viral oncoprotein inactivation of p53
4. Viral genetic differences are possible key to HIV dementia
5. Viral hitchhiker inhibits Wolbachia bacterias ability to proliferate
6. Viral protein helps infected T cells stick to uninfected cells
7. Viral fitness explains different resistance patterns to aids drugs
8. Viral protein influences key cell-signaling pathway
9. Research aims to identify markers for menopausal women at risk for deadly blood clot
10. Contributing membership in the biomarkers consortium surges to 30 companies and nonprofits
11. Cell receptor may lead to new biomarker for pancreatic cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/12/2019)... ... November 12, 2019 , ... In’Tech ... devices, today announced the creation of a Global Regulatory Affairs Department, to support ... industry is that the regulatory element to any Medtech organization is more important ...
(Date:11/12/2019)... ... November 12, 2019 , ... G5, the leader ... advertising performance up to 25% and reduces cost-per-click by as much as 15%. ... multi-touch attribution (MTA) to predict best advertising outcomes and automatically allocate daily ad ...
(Date:11/12/2019)... ... November 12, 2019 , ... Atlantic Ultraviolet Corporation (AUV), the ... distributors voted their patented automatic and manual wipers the #1 best feature of ... frequent maintenance task required of an ultraviolet water purifier is quartz sleeve cleaning. ...
Breaking Biology News(10 mins):
(Date:10/22/2019)... ... October 22, 2019 , ... DermBiont, a clinical stage microbiome ... met its primary safety endpoints, with no application site reactions and no adverse ... treatment of interdigital tinea pedis (athlete’s foot). Additionally, the trial demonstrated a clinical ...
(Date:10/17/2019)... ... October 16, 2019 , ... My Gene Counsel , ... published a new white paper that explores how frequently medical management guidelines have ... patients and medical providers can be kept informed as changes are made. , ...
(Date:10/10/2019)... BETHESDA, Md. (PRWEB) , ... October 09, 2019 ... ... announced Amy Abernethy, MD, PhD, Principal Deputy Commissioner, FDA, as a newly-confirmed ... place 27–30 October 2019 in Las Vegas, Nevada USA. , Dr. Abernethy, a ...
(Date:10/10/2019)... ... ... R3 Stem Cell announces it has added an exosome presentation to its upcoming ... spots still open. , The speaker, Dr. Ian White PhD, is a world renowned ... and Dartmouth. He currently serves as the Chief Scientific Officer at IMAC Regeneration Centers ...
Breaking Biology Technology:
Cached News: