HOME >> BIOLOGY >> NEWS
'Virtual' mouse brains now available online

ed by six institutions that form the Mouse Bioinformatics Research Network (MBIRN).

Those six schools -- Duke, the California Institute of Technology, the University of Tennessee at Memphis, the University of California at Los Angeles, Drexel College of Medicine and the University of California at San Diego -- are connected via a very high speed network with each other as well as with the San Diego Supercomputing Center.

The consortium has developed the computer infrastructure to collect a rapidly growing library of 3-D mouse brain data, and make all the data available on the web http://tinyurl.com/3cgj6z. The goal is to use mouse brains as surrogates for human brains to study the connections between genes and brain structure. Investigators from all over the world are sending their models to Duke where the 3-D images are acquired in a standardized fashion and made available via high speed web connections.

High resolution magnetic resonance imaging -- which the researchers call "MRI histology" provides distortion-free 3-D images with superb ability to distinguish subtle tissue differences in the brain, according to Johnson.

"The specimen is still actually in the skull," he said. "It hasn't been cut by a knife. It has not been dehydrated and distorted as it would be in conventional histological techniques."

Using computer-guided statistical methods, the data can be segmented into more than 30 anatomical structures with quantitative volume measurements. These structures can then be computer-enhanced to produce color-coded and labeled volume renderings of selected anatomical details in 3-D, seen at any angle.

MRI scanning is also quicker and costs less than conventional histology, he said. MRI histology permits study of an entire brain, which would be prohibitively expensive using conventional methods.

The Duke center has pioneered the development of MRI micro
'"/>

Contact: Monte Basgall
monte.basgall@duke.edu
919-681-8057
Duke University
9-Jul-2007


Page: 1 2 3

Related biology news :

1. OHSU turns mouse into factory for human liver cells
2. New approaches to endometriosis treatment -- mouse experiments point the way
3. New mouse model closely mimics human cancers
4. Statin treatment improves spatial memory in mouse models of Alzheimers
5. Treatment extends survival in mouse model of spinal muscular atrophy
6. UCSF stem cell study reveals cells capability in mouse brain tissue repair
7. Mutant mouse provides insights into breast cancer
8. Mapping the mouse genome
9. MRSA vaccine shows promise in mouse study
10. Researchers create mouse lacking key inflammation gene
11. U of MN researchers develop mouse model for muscle disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/31/2016)... PROVIDENCE, R.I. , March 31, 2016  Genomics ... leadership of founding CEO, Barrett Bready , M.D., ... addition, members of the original technical leadership team, including ... Vice President of Product Development, Steve Nurnberg and Vice ... have returned to the company. Dr. Bready ...
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... PROVO and SANDY, Utah ... Ontario (NSO), which operates the highest sample volume laboratory ... and Tute Genomics and UNIConnect, leaders in clinical sequencing ... announced the launch of a project to establish the ... panel. NSO has been contracted by ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... Calif (PRWEB) , ... May 03, 2016 , ... ... industry leading fertility clinics and IVF laboratories. A contingency of reproductive endocrinologists, including ... treat men and women experiencing infertility and to help them build families. , ...
(Date:5/2/2016)... ... May 02, 2016 , ... F.E.E.D. Co., the Feline ... their revolutionary, veterinarian-designed product for indoor cats. The NoBowl Feeding System replaces the ... food the way nature intended. NoBowls make cats happy and healthy. , Since ...
(Date:4/29/2016)... , April 29, 2016 ... Transparency Market Research "Separation Systems for Commercial Biotechnology ... Trends, and Forecast 2015 - 2023", the separation ... US$ 10,665.5 Mn in 2014 and is projected ... 2015 to 2023 to reach US$ 19,227.8 Mn ...
(Date:4/29/2016)... , April 29, 2016 ... the latest update to its industry-leading treatment planning software, ... that Monaco version 5.11 provides ... now attain calculation speeds up to four times faster ... . With the industry,s gold standard Monte ...
Breaking Biology Technology:
Cached News: