HOME >> BIOLOGY >> NEWS
'Virtual' mouse brains now available online

ed by six institutions that form the Mouse Bioinformatics Research Network (MBIRN).

Those six schools -- Duke, the California Institute of Technology, the University of Tennessee at Memphis, the University of California at Los Angeles, Drexel College of Medicine and the University of California at San Diego -- are connected via a very high speed network with each other as well as with the San Diego Supercomputing Center.

The consortium has developed the computer infrastructure to collect a rapidly growing library of 3-D mouse brain data, and make all the data available on the web http://tinyurl.com/3cgj6z. The goal is to use mouse brains as surrogates for human brains to study the connections between genes and brain structure. Investigators from all over the world are sending their models to Duke where the 3-D images are acquired in a standardized fashion and made available via high speed web connections.

High resolution magnetic resonance imaging -- which the researchers call "MRI histology" provides distortion-free 3-D images with superb ability to distinguish subtle tissue differences in the brain, according to Johnson.

"The specimen is still actually in the skull," he said. "It hasn't been cut by a knife. It has not been dehydrated and distorted as it would be in conventional histological techniques."

Using computer-guided statistical methods, the data can be segmented into more than 30 anatomical structures with quantitative volume measurements. These structures can then be computer-enhanced to produce color-coded and labeled volume renderings of selected anatomical details in 3-D, seen at any angle.

MRI scanning is also quicker and costs less than conventional histology, he said. MRI histology permits study of an entire brain, which would be prohibitively expensive using conventional methods.

The Duke center has pioneered the development of MRI micro
'"/>

Contact: Monte Basgall
monte.basgall@duke.edu
919-681-8057
Duke University
9-Jul-2007


Page: 1 2 3

Related biology news :

1. OHSU turns mouse into factory for human liver cells
2. New approaches to endometriosis treatment -- mouse experiments point the way
3. New mouse model closely mimics human cancers
4. Statin treatment improves spatial memory in mouse models of Alzheimers
5. Treatment extends survival in mouse model of spinal muscular atrophy
6. UCSF stem cell study reveals cells capability in mouse brain tissue repair
7. Mutant mouse provides insights into breast cancer
8. Mapping the mouse genome
9. MRSA vaccine shows promise in mouse study
10. Researchers create mouse lacking key inflammation gene
11. U of MN researchers develop mouse model for muscle disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/3/2017)... April 3, 2017  Data captured by ... platform, detected a statistically significant association between ... to treatment and objective response of cancer ... to predict whether cancer patients will respond ... as well as to improve both pre-infusion potency ...
(Date:3/30/2017)... KONG , March 30, 2017 The ... a system for three-dimensional (3D) fingerprint identification by adopting ground breaking ... into a new realm of speed and accuracy for use in ... at an affordable cost. ... ...
(Date:3/29/2017)... , March 29, 2017  higi, the health ... in North America , today announced ... and the acquisition of EveryMove. The new investment and ... set of tools to transform population health activities through ... lifestyle data. higi collects and secures data ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... , ... October 11, 2017 , ... Disappearing forests and ... lives of over 5.5 million people each year. Especially those living in larger cities ... Treepex - based in one of the most pollution-affected countries globally - decided to ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that ... Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los ...
(Date:10/10/2017)... , Oct. 10, 2017 SomaGenics announced ... the NIH to develop RealSeq®-SC (Single Cell), expected to ... profiling small RNAs (including microRNAs) from single cells using ... highlights the need to accelerate development of approaches to ... "New techniques for measuring levels of ...
(Date:10/9/2017)... (PRWEB) , ... October 09, 2017 , ... The award-winning ... to broadcast first quarter 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. ... is faced with the challenge of how to continue to feed a growing nation. ...
Breaking Biology Technology:
Cached News: