HOME >> BIOLOGY >> NEWS
'Virtual' mouse brains now available online

ed by six institutions that form the Mouse Bioinformatics Research Network (MBIRN).

Those six schools -- Duke, the California Institute of Technology, the University of Tennessee at Memphis, the University of California at Los Angeles, Drexel College of Medicine and the University of California at San Diego -- are connected via a very high speed network with each other as well as with the San Diego Supercomputing Center.

The consortium has developed the computer infrastructure to collect a rapidly growing library of 3-D mouse brain data, and make all the data available on the web http://tinyurl.com/3cgj6z. The goal is to use mouse brains as surrogates for human brains to study the connections between genes and brain structure. Investigators from all over the world are sending their models to Duke where the 3-D images are acquired in a standardized fashion and made available via high speed web connections.

High resolution magnetic resonance imaging -- which the researchers call "MRI histology" provides distortion-free 3-D images with superb ability to distinguish subtle tissue differences in the brain, according to Johnson.

"The specimen is still actually in the skull," he said. "It hasn't been cut by a knife. It has not been dehydrated and distorted as it would be in conventional histological techniques."

Using computer-guided statistical methods, the data can be segmented into more than 30 anatomical structures with quantitative volume measurements. These structures can then be computer-enhanced to produce color-coded and labeled volume renderings of selected anatomical details in 3-D, seen at any angle.

MRI scanning is also quicker and costs less than conventional histology, he said. MRI histology permits study of an entire brain, which would be prohibitively expensive using conventional methods.

The Duke center has pioneered the development of MRI micro
'"/>

Contact: Monte Basgall
monte.basgall@duke.edu
919-681-8057
Duke University
9-Jul-2007


Page: 1 2 3

Related biology news :

1. OHSU turns mouse into factory for human liver cells
2. New approaches to endometriosis treatment -- mouse experiments point the way
3. New mouse model closely mimics human cancers
4. Statin treatment improves spatial memory in mouse models of Alzheimers
5. Treatment extends survival in mouse model of spinal muscular atrophy
6. UCSF stem cell study reveals cells capability in mouse brain tissue repair
7. Mutant mouse provides insights into breast cancer
8. Mapping the mouse genome
9. MRSA vaccine shows promise in mouse study
10. Researchers create mouse lacking key inflammation gene
11. U of MN researchers develop mouse model for muscle disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... No two people are believed to ... York University Tandon School of Engineering and Michigan ... partial similarities between prints are common enough that ... and other electronic devices can be more vulnerable ... in the fact that fingerprint-based authentication systems feature ...
(Date:4/6/2017)... , April 6, 2017 ... RFID, ANPR, Document Readers, by End-Use (Transportation & Logistics, ... Facility, Oil, Gas & Fossil Generation Facility, Nuclear Power), ... Educational, Other) Are you looking for a ... sector? ...
(Date:4/5/2017)... -- Today HYPR Corp. , leading innovator in ... the HYPR platform is officially FIDO® Certified . ... that empowers biometric authentication across Fortune 500 enterprises and ... 15 million users across the financial services industry, however ... suites and physical access represent a growing portion of ...
Breaking Biology News(10 mins):
(Date:6/19/2017)... ... ... A colony of healthy honey bees is like a superorganism--individual bees provide the ... nutrients necessary for growth and survival. Better nutrition gives the colony a strong immune ... decline in honey bee health. Sick and weakened bees diminish the colony's resiliency, leading ...
(Date:6/15/2017)... ... June 15, 2017 , ... New resistant ... new options for managing Palmer amaranth and other broadleaf weeds resistant to glyphosate. ... are necessary. Auxin herbicides are known to drift and to cause harm to ...
(Date:6/15/2017)... ... June 15, 2017 , ... DuPont ... Biofuels, will be speaking at Bloomberg’s 2017 Sustainable Business Summit: Seattle ... environmental and sustainability officials on a panel titled “Developing a Corporate Renewables Strategy.” ...
(Date:6/14/2017)... ... June 14, 2017 , ... ... pumps and process equipment, has appointed Andrew Ondish as Territory Sales Manager for ... a B.S. degree in Petroleum Engineering from Colorado School of Mines. With nearly ...
Breaking Biology Technology:
Cached News: