HOME >> BIOLOGY >> NEWS
Vitamin E in plant seeds could halt prostate, lung cancer, says Purdue scientist

WEST LAFAYETTE, Ind. - The form of vitamin E found in many plant seeds - but not in most manufactured nutritional supplements - might halt the growth of prostate and lung cancer cells, according to a Purdue University study.

A team led by Qing Jiang (pronounced "ching zhang") has found that gamma-tocopherol, which occurs naturally in walnuts, pecans, sesame seeds, and in corn and sesame oils, inhibits the proliferation of lab-cultured human prostate and lung cancer cells. The vitamin's presence interrupts the synthesis of certain fatty molecules called sphingolipids, important components of cell membranes. However, the gamma-tocopherol leaves healthy human prostate cells unaffected, which could give it value as an anticancer agent.

"This is the first time gamma-tocopherol has been shown to induce death in lab-grown human cancer cells while leaving healthy cells alone," said Jiang, who is an assistant professor of foods and nutrition in the College of Consumer and Family Sciences. "This could be wonderful news for cancer patients if the effect can be reproduced in animal models. But because most nutritional supplements contain only alpha-tocopherol, a different form of vitamin E that alone does not have these anticancer properties, it may be better to supplement the diet with mixed forms of vitamin E. The study shows that the anticancer effect is enhanced when mixed forms are used."

Jiang's research appears in the current (week of Dec. 13) online edition of the scientific journal Proceedings of the National Academy of Sciences. She co-authored the paper with Jeffrey Wong, Henrik Fyrst, Julie D. Saba and Bruce N. Ames of the Children's Hospital Oakland Research Institute in Oakland, Calif.

Scientists have been studying vitamin E for more than three-quarters of a century, but most efforts have focused largely on alpha-tocopherol, one of eight known forms in the vitamin's family. Alpha-tocopherol was found early on to have the mo
'"/>

Contact: Chad Boutin
cboutin@purdue.edu
765-494-2081
Purdue University
14-Dec-2004


Page: 1 2 3

Related biology news :

1. Vitamin extends life in yeast, Dartmouth Medical School researchers find
2. Vitamin D, variations in its receptor and prostate cancer
3. Vitamin D deficiency widespread during pregnancy
4. Vitamin D3 provides the skin with protection from harmful microbes
5. Vitamin C and water not just healthy for people -- healthy for plastics, too
6. Vitamin D may cut pancreatic cancer risk by nearly half
7. Vitamin D and flavonoids examined for impact on breast and ovarian cancers
8. Nutritional friend or foe? Vitamin E sends mixed messages
9. Vitamin A analog is a potential lung cancer preventative with few side effects
10. Vitamin supplement could help treatment-resistant asthma
11. Vitamin As paradoxical role in influencing symmetry during embryonic development revealed

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/14/2016)... BioCatch ™, the global ... the appointment of Eyal Goldwerger as CEO. ... Goldwerger,s leadership appointment comes at a time of significant ... of its platform at several of the world,s largest ... unique cognitive and physiological factors, is a winner of ...
(Date:3/31/2016)... 31, 2016   ... the "Company") LegacyXChange is excited to release ... soon to be launched online site for trading 100% ... ) will also provide potential shareholders a sense of ... to an industry that is notorious for fraud. The ...
(Date:3/29/2016)... , March 29, 2016 ... "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are pleased to ... ink used in a variety of writing instruments, ensuring ... of originally created collectibles from athletes on LegacyXChange will ... analysis of the DNA. Bill Bollander ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... -- A person commits a crime, and the detective uses ... criminal down. An outbreak of foodborne illness makes ... uses DNA evidence to track down the bacteria that caused ... not. The FDA has increasingly used a complex, cutting-edge technology ... Put as simply as possible, whole genome sequencing is a ...
(Date:6/23/2016)... 2016   EpiBiome , a precision microbiome engineering ... debt financing from Silicon Valley Bank (SVB). The financing ... advance its drug development efforts, as well as purchase ... "SVB has been an incredible strategic partner to us ... bank would provide," said Dr. Aeron Tynes Hammack ...
(Date:6/23/2016)... 2016  Blueprint Bio, a company dedicated to identifying, ... community, has closed its Series A funding round, according ... "We have received a commitment from Forentis Fund ... to meet our current goals," stated Matthew Nunez ... to complete validation on the current projects in our ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... of intelligent tools designed, tuned and optimized exclusively for Okuma CNC machining centers ... The result of a collaboration among several companies with expertise in toolholding, cutting ...
Breaking Biology Technology:
Cached News: