HOME >> BIOLOGY >> NEWS
WHO data confirms low level of resistance to Tamiflu

New data published by the World Health Organisation (WHO) has confirmed a low frequency of resistance to Tamiflu (oseltamivir) over 3 influenza seasons (2003 2006)1.

The information, published by the Neuraminidase Inhibitor Susceptibility Network in the WHOs Weekly Epidemiological Record, has shown that resistance of around 0.3% to oseltamivir was seen during the influenza seasons in which there had been substantial Tamiflu use in Japan (35 million patients), the highest use in any market. This level of resistance is extremely low compared to rates of 65% seen in Japan with another antiviral, amantadine2.

"These results confirm that the potential for the development of resistance to Tamiflu is very low, even when used extensively in the management of seasonal influenza," commented Dr. David Reddy, Pandemic Task Force Leader, Roche. "This provides reassurance to the scientific community that since the introduction of Tamiflu in 1999, the levels of resistance have remained similar to those seen in the clinical development programme. Roche and the NISN continue to maintain high vigilance to keep on top of the evolving virus. "

Information gathering and results

As with any antiviral medication, there is a theoretical risk that a virus may emerge with decreased sensitivity to a drug. The Neuraminidase Inhibitor Susceptibility Network undertook screening for susceptibility to oseltamivir of influenza viruses randomly submitted to the national WHO Collaborating Centre for Reference and Research on Influenza and other Respiratory Diseases in Tokyo, Japan. Influenza virus isolates collected were tested by neuraminidase inhibition assay (IC50 or sequence analysis) to detect mutations associated with drug-resistance.

Results were as follows:

Influenza Season in Japan No of Influenza A isolates tested Resistance No of Influenza B isolates tested Resistance

2003/2004 1180 3 (0.3%) 171 0


'"/>

Contact: Lucy Rispin
lucy.rispin@ketchum.com
44-020-761-13621
Ketchum
9-May-2007


Page: 1 2 3

Related biology news :

1. Cornell lab confirms deadly fish virus spreading to new species
2. Study confirms the risk of exposure to secondhand tobacco smoke outdoors
3. FSU anthropologist confirms Hobbit indeed a separate species
4. Remote latrine reconfirms the presence of Essene sect at Qumran
5. Loma Linda University research confirms antioxidant-rich pecans protect against unhealthy oxidation
6. Study by LIJ obstetrician confirms taller women are more likely to have twins
7. Genetic surprise confirms neglected 70-year-old evolutionary hypothesis
8. Study confirms ammunition as main source of lead poisoning in condors
9. First human study confirms that immune cells can be a primary cause of bone loss in gum disease
10. Study confirms males/females use different parts of brain in language & visuospatial tasks
11. New method confirms importance of fungi in Arctic nitrogen cycle

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/2/2019)... ... ... Stay on top of current hot topics through free webinars presented by leading experts ... be sure to register today to save your place! Participate in the discussion and ... webinars: , CLINICAL OPERATIONS , November 14 – Leveraging Technology and Data to Establish ...
(Date:10/30/2019)... ... October 30, 2019 , ... ... Credit Knowledge Center in which participants will learn about precision agriculture tools used ... to these technologies. , Participants will have the opportunity to visit Virginia ...
(Date:10/30/2019)... ... 30, 2019 , ... Amberdata Inc., the leading blockchain and ... Capital, DF Capital, Rising Tide Fund, and HWVP. The new investment will ... its position as the leading data provider of institutional-grade blockchain and cryptoasset data. ...
Breaking Biology News(10 mins):
(Date:11/5/2019)... ... November 05, 2019 , ... Ole, a German Shepherd, was demonstrating signs of osteoarthritis ... jumping. Though his energy level and his willingness to play were normal, it was ... Holly Mullen of VCA Emergency Animal Hospital and Referral Center in San Diego, ...
(Date:10/30/2019)... ... October 30, 2019 , ... ... showcase the many roles innovation and technology play in educating the next generation ... featured hands-on learning opportunities and presentations by WesternU administrators and representatives of companies ...
(Date:10/22/2019)... ANGELES (PRWEB) , ... October 22, 2019 , ... nQ ... Graziadio Business School’s 2019 Most Fundable Companies List which was announced at a showcase ... than $10 million in annual revenue, strong business plans, and impressive near-term growth projections ...
(Date:10/17/2019)... ... October 16, 2019 , ... My Gene Counsel ... has published a new white paper that explores how frequently medical management guidelines ... how patients and medical providers can be kept informed as changes are made. ...
Breaking Biology Technology:
Cached News: