HOME >> BIOLOGY >> NEWS
When the villain becomes your friend: The strange tale of muscle lactate

In a paper published this week in The Journal of Physiology, Frank de Paoli and colleagues, working at the University of Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle.

In the late 19th century, fermentation chemists realized that juice left to ferment without adequate oxygen resulted in acid products. Then, in the early 20th century, when physiologists stimulated isolated frog muscles to contract until exhaustion, they found that the tissues had accumulated high amounts of lactic acid. Since then, the idea that lactic acid accumulation causes muscle fatigue has persisted. But did early scientists fail to address the various issues adequately and interpret the results appropriately" Did they fail to ask the essential question "Why does nature make lactic acid"", and did they in effect put one and one together and make them a minus"

De Paoli and colleagues looked at the effects of lactic acid and adrenaline on the processes that signal contractions in skeletal muscles. Using rat muscles, the study examined the combined effect of potassium ions, lactic acid and adrenaline on the electrical signalling system that serves to forward the activating signals from the brain to the muscle fibres where contraction takes place. They showed that in combination, lactic acid and adrenalin serve to help working muscles ward off the effects of potassium ions which leak from the inside to the outside of working muscle cells and negatively effect the signaling process by which muscles contract. In this, the latest of a series of reports from the Aarhus group, in combination with reports from other scientists in Scandinavia, the UK, US and Canada, long-standing ideas about the role of lactic acid in muscle are being overturned.

So, why do muscles contract" Usually, muscles contract because the central and peripheral nervous system signals them
'"/>

Contact: Melanie Thomson
melanie.thomson@oxon.blackwellpublishing.com
44-018-654-76270
Blackwell Publishing Ltd.
31-May-2007


Page: 1 2

Related biology news :

1. PNNL becomes DOE flagship for incentive-based waste management practices
2. Biological pest control becomes an economic reality
3. Medical steroids baffling connection to osteoporosis becomes clearer
4. Croatia becomes EMBL member state
5. Site of human-dolphin partnership becomes protected area
6. Gene expression becomes heterogeneous with age in humans and rats
7. Bionic fiction becomes science fact
8. Ferry-linked water monitoring system becomes new model for United States
9. AGI becomes founding partner of the International Year of Planet Earth
10. Common virus becomes a new target for cancer treatment
11. Study provides insights on why some prostate cancer becomes resistant to hormone withdrawl therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/12/2019)... ... November 12, 2019 , ... ... from nonprofit U.S. universities and research institutions for its Instrumentation Grant for ... up to $1.2 million per site for the acquisition of instrumentation, development and ...
(Date:11/7/2019)... (PRWEB) , ... November 07, 2019 , ... R3 Stem ... 50% off through the rest of 2019. The code to use during checkout is ... well. , R3 is the nation’s leader in regenerative therapies with over 12,000 successful ...
(Date:11/5/2019)... ... November 05, 2019 , ... Dr. Lauren Kopp ... dentistry to Seattle, WA, including porcelain veneers , smile makeovers, dental implants, ... University of Washington, Dr. Kopp is passionate about serving her Seattle community with ...
Breaking Biology News(10 mins):
(Date:11/5/2019)... ... November 05, 2019 , ... Focal Healthcare ... Mark for its Fusion Bx 2.0 prostate fusion biopsy solution. By combining information ... Bx 2.0 will give urologists across Europe the ability to perform targeted transrectal ...
(Date:11/2/2019)... ... 2019 , ... A clinical trial usually involves many different ... principal investigators, supply chain managers, manufacturers, IRT, CRAs and so on. Lack of ... data, potentially leading to patient risk. , By having a single source of ...
(Date:11/2/2019)... (PRWEB) , ... October 31, 2019 , ... ... released by pharma artificial intelligence pioneer tellic. drug360 brings tellic’s expertise in ... new tool allows researchers to quickly uncover relationships between genes, diseases, variants, phenotypes, ...
(Date:10/30/2019)... ... October 30, 2019 , ... Western University of ... innovation and technology play in educating the next generation of health care providers. ... and presentations by WesternU administrators and representatives of companies working with the University ...
Breaking Biology Technology:
Cached News: