HOME >> BIOLOGY >> NEWS
Women pregnant with girls experience more severe asthma symptoms

Women with asthma who are carrying a female fetus are more likely to experience worse asthma symptoms than asthmatic women carrying a male fetus, researchers at Yale School of Medicine report in the February issue of American Journal of Epidemiology.

"This is one of the first and largest studies to investigate the effect of fetal sex on the severity of the mother's asthma, and one of the largest to investigate the effect of fetal sex on any disease of the mother," said senior author Michael B. Bracken, Susan Dwight Bliss Professor of Epidemiology in the Department of Epidemiology and Public Health at Yale School of Medicine.

The researchers monitored 702 pregnant women throughout southern New England who were trained to assess their lung function for 10-day intervals at selected points in pregnancy. Lung function and a large number of other factors that might influence severity of the mother's asthma were recorded automatically.

Asthma worsened in mothers with either male or female fetuses until about 30 weeks gestation, after which there was an improvement in lung function. However, throughout pregnancy, mothers with a male fetus had 10 percent better lung function.

"This difference due to sex is potentially important but needs to be placed in the context of other factors which have a greater impact on the severity of mother's asthma, including inadequate medical management of asthma symptoms, and whether the mother was a smoker or not," said Bracken, who also co-directs the Yale Center for Perinatal, Pediatric and Environmental Epidemiology.

The authors speculate that testosterone, secreted by the male fetuses, may relax the mother's bronchial tissue and inhibit response to histamines. Other sex-specific factors excreted by female fetuses may aggravate inflammation in mothers. Bracken said more research is needed to test these hypotheses.

Asthma is one of the most common diseases associated with pregnancy. An up
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
2-Feb-2006


Page: 1 2

Related biology news :

1. Women up to age 30 at risk for bone loss, study finds
2. MBL scientist Julie Huber receives 2007 LOral USA Fellowship for Women in Science
3. Brandeis and Brigham and Womens Hospital license technology for Gauchers to Amicus Therapeutics
4. Women in polluted areas at higher risk of cardiovascular disease
5. Womens skin tone influences perception of beauty, health and age
6. Womens math performance affected by theories on sex differences: UBC researchers
7. Womens Bioethics Project unveils The Scientist & the Ethicist podcast series
8. Weizmann Women & Science Award presented to Dr. Mary-Claire King
9. Mary-Claire King to receive the 2006 Weizmann Women & Science Award
10. Womens health findings presented at national conference
11. Womens bioethics project receives grant from Ford Foundation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: