HOME >> BIOLOGY >> NEWS
World first: Scientists succeed in cloning human embryos from eggs matured in the lab

Copenhagen, Denmark: Scientists in Belgium have discovered how to clone human embryos from eggs that have been matured in the laboratory. Their discovery should make it easier for scientists to create embryonic stem cell lines from cloned embryos and develop them to provide eggs and sperm for infertile couples, the 21st annual conference of the European Society of Human Reproduction and Embryology heard today (Monday 20 June).

Until now, scientists investigating human cloning for therapeutic purposes have been limited to using mature eggs (oocytes) that have reached the metaphase II stage (MII) at which ovulation and fertilisation occurs in humans. However, there are few human MII oocytes available for research because almost all that are retrieved from women seeking fertility treatment are used to treat the patient. Immature oocytes are not used routinely for treatment at present, and so any that are retrieved can be donated for research. These immature oocytes are arrested in the prophase I stage, before meiotic division is complete, when the enlarged nucleus is called the germinal vesicle (GV).

Bjorn Heindryckx, a PhD student at the Infertility Centre at Ghent University Hospital, Belgium, and his colleagues, matured GV oocytes in culture in the laboratory for 44 hours, after which time 85% of the GV oocytes had developed into MII oocytes. From each of these, they removed the nuclear apparatus, which contained the chromosomes that held all the genetic information. Using conventional ICSI techniques, they injected into the empty oocytes the nuclei taken from somatic cumulus1 cells (i.e. non-germ cells) of another person a process known as non-autologous nuclear transfer. After time for nuclear re-programming the oocytes were artificially activated by incubation in a medium containing calcium ionophore, which enabled the injected nucleus to prepare for the first embryonic division.

Mr Heindryckx said: "Eighteen out of the 25 in vitro
'"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
20-Jun-2005


Page: 1 2 3

Related biology news :

1. World Wildlife Fund warns against iron dumping experiment near the Galapagos Islands
2. Worlds first X-ray free electron laser is on course to completion
3. Worlds leading scientists announce creation of Encyclopedia of Life
4. Prize winners announced at ISNs World Congress of Nephrology
5. World first test potential to identify breast cancer patients who will react badly to radiotherapy
6. Worlds top engineers in San Antonio for system of systems conference
7. OneWorld Health selects Odyssey Research for phase 4 study in India
8. MicrobeWorld podcast wins another award
9. International Astronautical Federation joins project to protect World Heritage sites
10. Press registration -- World Congress of Nephrology, April 21-25, 2007, Rio de Janeiro, Brazil
11. Nature Genetics and the International Society of Nephrology come to Danvers on World Kidney Day

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... (PRWEB) , ... July 01, 2020 , ... ... presented its phase 1a findings of Neihulizumab, a biologic for the treatment of ... June 2020. Led by hemato-oncologist Dr. Paul J Martin of the Fred Hutchinson ...
(Date:6/28/2020)... BASEL, Switzerland (PRWEB) , ... ... ... leading provider of enterprise software solutions for biopharmaceutical R&D, today announced that ... oncology company developing innovative, full-length multispecific antibodies (Multiclonics®), to support their translational ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... healthcare, and Renovagen Ltd, a UK supplier and manufacturer of innovative portable renewable ... testing operations in the fight against the COVID-19 pandemic in Zambia. , One ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... (PRWEB) , ... June 29, 2020 , ... ... year to date growth of 40% in 2020, despite many obstacles created as ... MedShift aims to increase revenue for its partnered medical practices and medical manufacturers ...
(Date:6/28/2020)... ... June 25, 2020 , ... Lumeda Inc. ... today announced the company has entered a license agreement with Roswell Park Comprehensive ... globally exclusive rights to Roswell Park intellectual property surrounding a novel medical device ...
(Date:6/23/2020)... YORK (PRWEB) , ... June 22, 2020 , ... ... its lead glutamine antagonist, DRP-104, will be presented June 22-24 during the American ... effects of DRP-104; and, the other profiles the potent, consistent single agent activity ...
(Date:6/11/2020)... GREENBELT, Md. (PRWEB) , ... June 09, 2020 ... ... announced today the release of the NEON Micro-Tracer Solution, a highly ... to the COVID-19 virus in the workplace. Contact tracing, a core disease control ...
Breaking Biology Technology:
Cached News: