HOME >> BIOLOGY >> NEWS
World-first stem cell research could aid male infertility

Scientists have shown for the first time that sperm grown from embryonic stem cells can be used to produce offspring.

The experiment was carried out using mice and produced seven babies, six of which lived to adulthood.

The breakthrough, reported today, Monday July 10, in the academic journal Developmental Cell, helps scientists to understand more about how animals produce sperm. This knowledge has potential applications in the treatment of male infertility.

Karim Nayernia, who has just taken up a post as Professor of Stem Cell Biology at Newcastle University, led the research while in his previous position at Georg-August University in Gttingen, Germany, with Prof. Dr Wolfgang Engel and colleagues from Germany and the UK, including Dr. David Elliott from Newcastle University's Institute of Human Genetics.

Stem cells have the potential to develop into any tissue type in the body and could therefore be used to develop a wide range of medical therapies.

Prof Nayernia, of the Newcastle-Durham-NHS Institute for Stem Cell Biology and Regenerative Medicine*, and his team describe in their paper how they developed a new strategy for generating mature sperm cells in the laboratory using embryonic stem cells from mice. They then went on to test whether this sperm would function in real life.

The team isolated stem cells from a blastocyst, an early-stage embryo that is a cluster of cells only a few days old.

These cells were grown in the laboratory and screened using a special sorting machine. Some had grown into a type of stem cell known as 'spermatogonial stem cells', or early-stage sperm cells.

The spermatogonial cells were singled out, then genetically marked and grown in the laboratory. Some of them grew into cells resembling sperm, known as gametes, which were themselves singled out and highlighted using a genetic marker.

The sperm that had been derived from the embryon
'"/>

Contact: Claire Jordan
press.office@ncl.ac.uk
191-222-7850
University of Newcastle upon Tyne
10-Jul-2006


Page: 1 2 3

Related biology news :

1. World-first technology enables study of ancient bacteria
2. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
3. Saudi Arabias KAUST names WHOI first research partner
4. Multinational research: protecting ecology means understanding people, too
5. Newly created cancer stem cells could aid breast cancer research
6. Carnegie Mellons Peter Adams receives EPA research grant
7. Almac Diagnostics announces pioneering genetic research on ductal carcinoma in situ
8. Innovative tagging technique may help researchers better protect fish stocks
9. Penn researchers discover how key protein stops inflammation
10. UCF research links proteins, stem cells and potential Alzheimers treatment
11. ASU researchers partner with UOP to make biofuel for military jets a reality

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... LAKE CITY, and MARTINSRIED, Germany (PRWEB) , ... ... ... in high-throughput antibody screening and characterization, announced today that they have opened a ... Carterra’s platform has fueled the need for the new office. , The Munich ...
(Date:8/14/2019)... ... ... Representatives with MyBioGate announced that China Focus@Biotech Week will be held September ... projects connect with Chinese pharma and investors in healthcare innovation,” said Miao Guo, Vice ... as a part of Biotech Week Boston – the annual biotech festival at the ...
(Date:8/14/2019)... TORONTO (PRWEB) , ... August 13, 2019 , ... ... Cancer Medicine Team, Division of Molecular Pathology, Institute of Cancer Research (ICR) in ... (5pm BST/UK) to learn about the process of biomarker and companion diagnostic development ...
Breaking Biology News(10 mins):
(Date:8/14/2019)... Pa. (PRWEB) , ... August 13, 2019 , ... ... nuclear receptor and in vitro toxicology testing solutions, announced the appointment of Mark ... industry experience to the Board. , Mark McLoughlin will lend his healthcare expertise ...
(Date:8/7/2019)... ... ... Locus Agricultural Solutions (Locus AG) reports record levels of carbon sequestered in ... ® , which is pulling up to 121% more carbon into the soil than ... from the treatment of almonds, cherries, turf/sod, grapes and citrus across the U.S., as ...
(Date:8/6/2019)... , ... August 05, 2019 , ... ... Casarella has been recognized as a distinguished leader by PharmaVOICE magazine, earning him ... an article in the magazine’s July/August special issue. , As the executive vice ...
(Date:7/30/2019)... ... July 30, 2019 , ... The summer season has ... company. Not only has the company already hosted many of its signature cooking ... to its guests. , With Lajollacooks4u’s Private Cooking Parties, guests prepare and enjoy ...
Breaking Biology Technology:
Cached News: