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Worlds oldest, largest organization of cancer scientists favors 'full spectrum of stem cell research biology'

c stem cells have the ability to transform into the cells of every major organ system in the human body. If this characteristic can be controlled, then medical researchers could determine the signals that direct the development of human tissues, including cancers.

  • Bone marrow stem cells already have demonstrated their value in replenishing blood and immune systems damaged by cancer or cancer treatment. Research on human embryonic stem cells may extend this promise by providing a transplantable cell source that avoids the problems of immune rejection.

  • Cancer stem cells have been described as the progenitors of breast, prostate, brain and other malignant tumors, raising the prospect of eliminating tumor recurrence following initial treatment and developing cancer therapies that are truly curative.

  • Embryonic stem cells' ability spontaneously to form tumors should not hinder the progress of stem cell research, since these cells will be used only as precursors to the differentiated cells needed to replenish damaged tissue.

    In light of the recent cloning of patient-specific human embryonic stem cells by researchers in South Korea, AACR Science Policy and Legislative Affairs Committee Chairman William G. Nelson V, M.D., Ph.D., pointed to the clause in the AACR position statement encouraging grant-making institutions to "work toward stable and sufficient funding for meritorious stem cell projects, free of political uncertainty, so that young investigators are encouraged to devote their careers to this important field."

    Said Nelson, professor in the departments of Oncology, Urology, Pharmacology and Molecular Sciences, Medicine, Pathology, and Radiation Oncology and Molecular Radiation Sciences, at Johns Hopkins University, "The United States is so closely associated with scientific advancements that the first question on everyone's mind was, 'why wasn't this huge medical breakthrough made by Americans?'

    "Sadly
    '"/>



    • Contact: Elizabeth Tait
    tait@aacr.org
    215-440-9300
    American Association for Cancer Research
    13-Jul-2005


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