X-chromosome tells the tale

HOUSTON (March 17, 2005) If the human genome is indeed the "book of life," then the X-chromosome is all plot.

In a report in today's issue of the journal Nature, a host of genome researchers describe the nature of this mysterious "chapter" in the DNA story.

"Large numbers of medically related genes happen to fall on the X," said Dr. Steven Scherer, associate professor in the Baylor College of Medicine department of molecular and human genetics and director of mapping in the BCM Human Genome Sequencing Center. "For a chromosome that is so bereft of genes compared to other chromosomes, this one is well characterized with regard to disease genes."

The fact that men have just one copy of the X chromosome makes the mutated genes on that one piece of DNA much easier to find, said Scherer.

Scherer and his colleagues in the BCM Sequencing Center were the number two contributors to the sequencing effort directed at the X chromosome. It was led by the Wellcome Trust Sanger Institute in Britain.

The story of each chromosome will be published eventually, with all the important features explained, said Scherer.

"I expect this chromosome is the all-star of the series. It will make interesting reading for the general scientific population and the lay public," he said. "If you were going to read a chromosome paper, this probably ought to be the one you read."

The role of the X and Y chromosomes have evolved. Before the split between birds and mammals, the X and Y chromosomes were just like any other pair of chromosomes each was fairly similar and carried similar information.

The authors, in tracing the evolution of the X chromosome, showed that slowly, but surely, the Y chromosome "dropped off the face of the earth," said Scherer. "Although it contains a few important genes, it's almost like the appendix of the human genome."

Every woman has two X chromosomes. Each man has an X chromosome and a Y chromos

Contact: Ross Tomlin
Baylor College of Medicine

Page: 1 2

Related biology news :

1. Exercise pill switches on gene that tells cells to burn fat
2. Ancient coral reef tells the history of Kenyas soil erosion
3. Mapping system tells skin cells whether to become scalp, palm tissues, Stanford study finds
4. Scent of a woman tells male redback spiders to find a mate
5. Microbiology text tells stories, offers online resources
6. Pall tells FDA panel about blood filtering technology
7. Researchers find gland that tells fruit flies when to stop growing
8. Its a bugs life: MIT team tells moving tale
9. Immune systems distress signal tells bacteria when to strike back
10. DNA from feathers tells tale of eagle fidelity
11. As the protein folds: The tail of the gene tells the tale of Machado-Joseph disease

Post Your Comments:

(Date:8/21/2020)... ... August 19, 2020 , ... The 19th ... life science, data science, informatics and IT leaders goes VIRTUAL and announces its ... uncertainty and change, Bio-IT takes the leadership role of keeping our life science ...
(Date:8/12/2020)... SEATTLE (PRWEB) , ... August 12, 2020 , ... ... tracking and monitoring systems that are ideal for public health agencies of all ... containing contagious diseases and helping at-risk individuals find appropriate health care, Mosio helps ...
(Date:8/5/2020)... ... 05, 2020 , ... Regenative Labs has received approval from the Centers for ... them the first Wharton’s jelly allografts to be assigned a Q code and be ... the first Wharton’s jelly allograft product to be recognized as a 361 HCT/P by ...
Breaking Biology News(10 mins):
(Date:7/1/2020)... ... June 29, 2020 , ... The Interlocal Purchasing ... to its membership, recently named BioFit Engineered Products an Awarded Vendor. ... purchase ergonomic seating, cafeteria tables, book trucks and carts at discounted pricing without ...
(Date:6/28/2020)... ... 25, 2020 , ... The Indoor Lab, a leading provider of sensor solutions ... all types to ensure cleanliness, distancing and occupancy with its patent pending WipeAway™ technology ... business will provide a health performance index system that scores all aspects of compliance ...
(Date:6/28/2020)... Conn. (PRWEB) , ... June 25, 2020 , ... ... formed to advance photodynamic therapy for treating cancer, today announced the company has ... York (“Roswell Park”). The agreement provides Lumeda globally exclusive rights to Roswell ...
(Date:6/23/2020)... ... 2020 , ... Kerafast Inc. , developers of an ... availability of the Delta-G-VSV Pseudotyping System for coronavirus research applications. The system, developed ... viral entry and COVID-19 vaccine effectiveness at just biosafety level 2 (BSL-2) containment. ...
Breaking Biology Technology:
Cached News: