HOME >> BIOLOGY >> NEWS
Yale researchers use laser light to remote control flies

New Haven, Conn. Scientists at Yale have genetically designed triggers in the brains of fruit flies that allow the flies' behavior to be controlled with laser light, according to an article in the April 8 issue of the journal Cell.

In some experiments the light controls were engineered to alter how the flies jump, beat their wings and fly in an escape response. In other experiments, the light controls were used to activate dopamine neurons that stimulated walking and affected the types of paths the flies chose to follow. Loss of dopamine cell activity in humans underlies Parkinson's disease, a movement disorder.

Unfocused laser light was used to "broadcast" the signal to genetically engineered "phototriggers" that were expressed only in specific groups of cells. Changing conditions of the light pulses altered the activity level of the flies and the direction of their flight. These responses to laser light demonstrated a direct link between specific neurons and specific behaviors.

Gero Miesenbck, associate professor of cell biology at Yale, and principal investigator of the study, explained that the photoreceptors are ion channels that spark action potentials when illuminated. Depending on which neurons are light-sensitive, the remote-controlled flies jump, fly or change their walking patterns on command.

"The ability to control brain functions non-invasively opens many new possibilities for the analysis of neural circuits, the search for the cellular substrates of behavior, and, possibly even restoring function after injury or disease," said Miesenbck "This is a significant step toward moving neuroscience to active and predictive manipulation of behavior."

But, is it mind control? The authors demonstrate that even headless flies take mindful flight if the correct set
'"/>

Contact: Janet Rettig Emanuel
janet.emanuel@yale.edu
203-432-2157
Yale University
7-Apr-2005


Page: 1 2

Related biology news :

1. Innovative tagging technique may help researchers better protect fish stocks
2. Penn researchers discover how key protein stops inflammation
3. ASU researchers partner with UOP to make biofuel for military jets a reality
4. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
5. Penn researchers discover pathway that eliminates genetic defects in red blood cells
6. U-M researchers find family of on switches that cause prostate cancer
7. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
8. Pets could be source of multiresistant bacteria infections in humans, MU researchers investigate
9. MGH researchers confirm that bone marrow restores fertility in female mice
10. Smithsonians National Zoo researchers use electronic eggs to help save threatened species
11. U-M researchers identify gene involved in breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at http://www.nxt-id.com ... http://www.sec.gov . 2016 Year Highlights: ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS announces ... addition of its newest module, US Hemostats & Sealants. , SmartTRAK’s US Market ... hemostats, fibrin sealants, synthetic sealants and biologic sealants used in surgical applications. BioMedGPS ...
(Date:10/11/2017)... ... October 11, 2017 , ... Personal eye wash is a basic first aid supply ... a time. So which eye do you rinse first if a dangerous substance enters both ... Duo Eye Wash with its unique dual eye piece. , “Whether its dirt and ...
(Date:10/11/2017)... ... October 11, 2017 , ... Disappearing forests and increased ... of over 5.5 million people each year. Especially those living in larger cities are ... - based in one of the most pollution-affected countries globally - decided to take ...
(Date:10/10/2017)... ... October 10, 2017 , ... For the ... won a US2020 STEM Mentoring Award. Representatives of the FirstHand program travelled to ... Experience from US2020. , US2020’s mission is to change the trajectory of STEM ...
Breaking Biology Technology:
Cached News: