accine research is exciting to scientists because preliminary data indicate that it is a means to prevent cancer of the cervix. In developing countries this would be lifesaving, as few women have access to the Pap smear, an effective early screening method that has significantly reduced the rate of cervical cancer in the United States in the past 50 years. "We are getting closer to eradicating cervical cancer" through prevention, Giuilano says.

HPV is the most common sexually transmitted infection in the United States. It affects the skin in the genital area as well as the anal canal. Condoms do not protect against HPV and the infection can lead to genital warts. To date, there is no cure for HPV. HPV is passed from one person to another by contact with infected skin, frequently during sex. HPV infects the penis or the female genitals where is often remains unseen but can be carried to unsuspecting partners during sex.

In men, genital warts appear as growths or bumps on the penis, scrotum, in or around the anus, or groin. Warts may be raised or flat, single or multiple, small or large. Sometimes they are so small that they can't be seen by the naked eye. Some people only have one episode of genital warts, while others have recurrences. In a small percentage of men, infection with certain HPV types will result in precancer or cancer of the penis or the anal canal.

The Mexican study site is Cuernavaca; the Brazilian is So Paulo. Men in Florida who wish to volunteer for the study trial should call (813) 745-6996.

Giuliano's other research interests include cancer epidemiology biomarkers, nutritional supplements and diet in risk reduction, breast cancer and cancer screening. She left the University of Arizona to join Moffitt and USF in July 2004.

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Contact: Andrea Brunais
MediaRelations@moffitt.usf.edu
813-632-1478
University of South Florida Health
1-Feb-2005

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