The ACRN a partnership of NHLBI, eight clinical centers across the United States, and the Data Coordinating Center at Penn State College of Medicine was initiated in 1993 with the goal of conducting well-designed clinical trials for rapid evaluation of new and existing treatments for asthma. Since 1993, ACRN has completed eight multi-center clinical trials in adult asthma with three others in progress.
As Data Coordinating Center, the Penn State College of Medicine team led by principal investigator Vernon M. Chinchilli, Ph.D., distinguished professor and interim chair of health evaluation sciences, provides expertise in biostatistical design and analysis, scientific coordination, data management, administration, and research computing for all of the ACRN's clinical trials.
"The ACRN has played a significant role in reducing the impact of asthma morbidity and mortality and we are proud to have been one of the original partnering institutions," Chinchilli said. "This significant grant allows us to continue providing expertise to our clinical partners across the country and to contribute to the evaluation of novel therapies to help the more than 20 million people in the United States who suffer from asthma."
The Data Coordinating Center team has developed a unique data management system to support the collection, verification and reporting of clinical data. Asthma patients who agree to participate in an ACRN clinical trial visit one of the clinical centers where medical staff take respiratory response measurements. In addition, patients record their symptoms, medication use and at-home respiratory measure
Contact: Valerie Gliem