New Substance, Found In Patent, May Help With Asthma, Migraine, And Pain Treatments

COLUMBUS, Ohio--Chemical Abstracts Service added the 18 millionth chemical substance to its database--the world's largest collection of chemical information. The substance, identified in a patent application from Merck and Co., is an intermediate compound in the preparation of tachykinin receptor antagonists which may be useful in the treatment of inflammatory diseases, pain or migraine and other ailments.

The substance's name is (1S-cis)-2-Phenyl-3-cyclohexene-1-carboxylic acid and it is identified by the CAS Registry Number 207110-49-4.

Chemical Abstracts Service reviews and summarizes chemistry research in patents, conference proceedings and more than 8,000 scientific journals; in the process, CAS scientists identify new chemical substances mentioned in new scholarly reports, and capture them in the CAS Registry file.

New chemical substances are added to the CAS Registry at the rate of approximately one new record every 9 seconds. (The great majority of chemical substances mentioned in scientific literature are never encountered by the general public, nor produced in significant quantities. Nevertheless, some of these substances may eventually lead to new medicine, materials, or other important discoveries.)

The 18 millionth substance was registered on June 15, 1998, selected from a World Intellectual Property Organization patent application of April 30, 1998 from Merck & Co., Inc.

Chemical Abstracts Service is a division of the American Chemical Society, the world's largest scientific society, with a membership of more than 155,000 chemists and chemical engineers. CAS has published Chemical Abstracts since 1907.

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Contact: Kirk Monroe
k_monroe@acs.org
202/872-4445
American Chemical Society
22-Jun-1998