2005 Salivary Research Award

Baltimore, Maryland...Dr. J. David Castle, from the University of Virginia Health Science Center, Charlottesville, is the recipient of the 2005 Salivary Research Award from the International Association for Dental Research (IADR), convening here today for its 83rd General Session. The award was designed to stimulate and recognize outstanding and innovative achievements that have contributed to the basic understanding of salivary gland structure, secretion, and function, or salivary composition and function.

Dr. Castle has devoted his scientific career to elucidating the mechanism of secretion from exocrine cells, in particular salivary glands, and throughout his career he has made many novel and important contributions that have had a highly significant impact on our understanding of the molecular mechanisms of exocytosis. These include analysis of secretory granules and their membrane components; demonstration of a proton pump in secretion granules, the role of pH in aggregation of protein in the granules as well as removal of other ions in condensation of granule content, and salivary-gland-specific proline-rich proteins that play a role for their sorting into secretion granules. These studies have led to the more general conclusion that there is no common module in secreted proteins that ensure their sorting into secretion granules, and that this process therefore is of a passive nature.

In recent years, there has been intense interest in membrane trafficking in the cell and the process whereby the fusion of secretion granules and cell membranes occurs, and proteins such as v-SNAREs and t-SNAREs have been identified. Dr. Castle has contributed significantly to this field with his discovery of a new family of proteins--named SCAMPs--occurring widespread in different mammalian tissues that may be important in a late step in exocytosis.

Dr. Castle is also responsible for demonstrating a total of four pathways of secretion in parotid cells--the constitu

Contact: Linda T. Hemphill
International & American Association for Dental Research

Page: 1 2

Related medicine news :

1. 2004 Salivary Research Award to Ekstrom
2. Researchers search for first sign of congestive heart failure
3. Research offers hope of new treatments for liver damage
4. Research suggests possible blood test for multiple sclerosis
5. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
6. 2005 Award for Basic Research in Biological Mineralization
7. 2005 Craniofacial Biology Research Award
8. 2005 Research in Dental Caries Award
9. 2005 Research in Prosthodontics and Implants Award
10. 2005 Basic Research in Periodontal Disease Award
11. 2005 Research in Oral Biology Award

Post Your Comments:

(Date:9/1/2020)... Calif. (PRWEB) , ... September 01, 2020 , ... ... a new practice in Glendale. While the office will be the ... as breast augmentation, tummy tucks, buttock augmentation (Brazilian butt lift), as well as ...
(Date:9/1/2020)... Calif. (PRWEB) , ... September 01, 2020 , ... As ... “safe side”, the Cohn Health Institute has taken this time to expand ... celebration of its 30th Anniversary, the Cohn Health Institute will be relaunching its brand ...
(Date:8/31/2020)... ... August 31, 2020 , ... The ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... 10th Anniversary of Blood Cancer Awareness Month (BCAM) and its international Light ...
(Date:8/31/2020)... ... August 31, 2020 , ... Want to get moving, break up your ... Foundation (CPARF) is thrilled to launch its fourth annual STEPtember campaign in the United ... STEPtember meets everyone wherever they are at this moment — encouraging people to move ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... to dental groups in the United States, today announced the grand opening of ... CA. , Patients will enjoy convenient hours, a comfortable office, and full-service ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... Neil ... serve as Secretary to the Board of Trustees and committee chair of the ... Way is a Denver-based nonprofit organization that fights for the education, health, and ...
(Date:9/1/2020)... ... 01, 2020 , ... September is National Ovarian Cancer Awareness Month. Ovarian ... other cancer of the female reproductive system. The American Cancer Society estimates that ... women will die from this disease. Throughout the month of September, Women’s Excellence ...
(Date:8/31/2020)... ... August 31, 2020 , ... Continuing on its rapid ... sanitization, disinfection and deodorization provider - is proud to announce it has opened ... for businesses and residents throughout the area. , Germinator provides a 100% safe ...
Breaking Medicine Technology:
Cached News: