A Note of Caution: Be Careful When Mixing Grapefruit Juice With Rxs

maceutical Scientists, professor of Biopharmaceutical Sciences at UCSF and director of the study. Patients already taking grapefruit juice with their medications can continue to do so. However, for certain drugs we studied, such as immunosuppressives and HIV protease inhibitors, patients may get a further increase in absorption by taking their drugs a couple of hours after a glass of grapefruit juice.

According to Dr. Benet, Patients who have not previously taken their drugs with grapefruit juice should be very cautious in doing so, since we now recognize, depending on the drug, that grapefruit juice may either increase or decrease levels of drug in the blood, leading to potential concerns for toxicity or lack of efficacy.


Contact: Valerie Breslow
American Association of Pharmaceutical Scientists

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