HOME >> MEDICINE >> NEWS
A leading cause of preventable blindness may be controlled by simple course of oral antibiotic

Treating entire communities with the oral antibiotic azithromycin might effectively control an infection that causes widespread eye disease in developing countries, according to a new study.

The eye disease is trachoma, one of the world's leading causes of preventable blindness. Research results show oral treatment to be markedly better in reducing the number of infections than topical therapy, which uses an ointment form of the antibiotic tetracycline. Public health programs historically used the topical ointment for treatment and control of trachoma.

"We have known for decades that we had the antibiotics to successfully treat this disease when cases developed, but we didn't seem to have the right drug delivery method to control the bug over time. Now we know that we do, and we are very excited at the promise of these results," said Julius Schachter, PhD, professor of laboratory medicine at the University of California San Francisco and lead investigator of the study.

"Although azithromycin costs more than tetracycline ointment, the expense may be offset by the higher costs of distributing and administering multiple doses of the ointment," added Schachter, who also is director of the UCSF Chlamydia Research Laboratory at San Francisco General Hospital Medical Center. Study findings are reported in the August 21st issue of the British medical journal, The Lancet.

Researchers compared the effect of the two antibiotic regimens on infection rates in villages located in trachoma endemic areas where transmission of infection is high. The villages were in the African countries of Egypt, The Gambia, and Tanzania.

Previous studies have shown that topical antibiotics reduced the severity of disease and infection levels for the short-term, but they did not control trachoma levels over the long-term.

Trachoma occurs when the bacterium Chlamydia trachomatis infects the inner eyelid. The disease persists in staggering numbers in developing countr
'"/>

Contact: Rebecca Sladek Nowlis
rsnowlis@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
20-Aug-1999


Page: 1 2 3

Related medicine news :

1. Public morally obliged to take part in scientific research, says leading ethicist
2. New guideline tackles leading cause of mother and child death
3. Breast implant Website launched by leading plastic surgery societies
4. Small increases or blips in HIV levels do not signal mutations leading to drug-resistant HIV
5. Government approach to cutting hospital stays may be misleading
6. Thanks for the memories: cinematic portrayal of amnesia is profoundly misleading
7. Money issues leading cause of holiday stress for Americans
8. Tar measurements on cigarette packets are misleading
9. Researchers discover new clinical syndrome leading to severe osteoarthritis
10. Lung cancer now leading cause of cancer death in women
11. Mechanism leading to life-threatening infection identified by UCSD School of Medicine researchers

Post Your Comments:
(Date:9/3/2015)... ... September 03, 2015 , ... E-Volve Health, ... leading national healthcare solutions organization, to provide electronic medical record (EMR) consulting services ... Amerinet members will receive negotiated pricing on E-Volve Health’s Epic EMR consulting, custom ...
(Date:9/3/2015)... ... September 03, 2015 , ... Mayo ... Indianapolis, have chosen Center for Hospice Care (CHC) for physician Hospice and ... at CHC as part of fulfilling their requirements for obtaining national Board Certification ...
(Date:9/3/2015)... ... 2015 , ... DriButts, a non-profit organization dedicated to helping ... Group to manufacture a long-lasting reusable diaper for warm weather climates where there ... 600 DriButts Diapers to rural areas of Haiti during a trip scheduled for ...
(Date:9/3/2015)... ... September 03, 2015 , ... Results of a ... Healthcare Research and Policy Analysis has found physician leadership development training programs to ... percent of respondents said their organizations conduct some kind of physician leadership development ...
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... ... care community to be situated at 4400 Columbine Drive in Bellingham, Washington. Silverado ... 2016, and has been carefully designed to serve up to 80 people living ...
Breaking Medicine News(10 mins):Health News:E-Volve Health to Offer EMR Consulting Solutions to Amerinet Members 2Health News:Physicians from Mayo Clinic and Indiana University to Complete Hospice & Palliative Medicine Training at Center for Hospice Care 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 2Health News:DriButts Diapers Rely on Slingshot Help in Haiti 3Health News:Survey finds growing movement for physician leadership training 2Health News:Survey finds growing movement for physician leadership training 3Health News:Site Dedication Ceremony to Celebrate New Silverado Memory Care Community 2
(Date:9/3/2015)... 2015 Research and ... of the "Global Craniomaxillofacial (CMF) Devices Market ... The global craniomaxillofacial devices market to grow at ... report covers the present and future scenario of ... calculate the market size, we use revenues generated ...
(Date:9/3/2015)... , Sept. 3, 2015 HeartWare International, ... of less invasive, miniaturized circulatory support technologies that are ... that its President and Chief Executive Officer, Doug ... Wells Fargo Healthcare Conference at 8:50 a.m. ET on ... 9-10, 2015 at The Hyatt Regency, Boston ...
(Date:9/3/2015)... Sept. 3, 2015 Research and Markets ( ... "Investigation Report on China Olmesartan Market, 2010-2019" report ... medoxomil was successfully developed by Sankyo Pharmaceuticals Co., Ltd ... olmesartan medoxomil was approved by FDA to enter the ... best- selling drug in the world after it succeeded ...
Breaking Medicine Technology:Global Craniomaxillofacial (CMF) Devices Market 2015-2019 - Product Innovation and Cost Reduction a Key Market Trend 2HeartWare Presentation At The 2015 Wells Fargo Healthcare Conference To Be Webcast 2China Olmesartan Investigation Market Report 2010-2019 2
Cached News: