HOME >> MEDICINE >> NEWS
A nicotine by-product reacts with proteins, say scientists at TSRI

the development of these advanced glycation endproducts.

When they tested the blood of smokers and non-smokers, they found that the smokers had higher levels of the nornicotine-modified proteins than non-smokers. The smokers also had higher levels of the advanced glycation endproducts.

The persistence of nornicotine in the bloodstreamas opposed to nicotine, which quickly disappears after cessation of smokingmay also suggest a role for nornicotine in contributing to the biological mechanisms of tobacco addiction, since the nornicotine provides a long-lived source of nicotine-like molecules.

The work highlights the need for more studies into the consequences of exposing the human body to nicotine metabolites, like nornicotine.

The article, "A previously undescribed chemical link between smoking and metabolic disease" was authored by Tobin J. Dickerson and Kim D. Janda and appears in the October 28, 2002 online edition of the journal Proceedings of the National Academy of Sciences. The article will appear in print later this year.


'"/>

Contact: Jason Bardi
jasonb@scripps.edu
858-784-9254
Scripps Research Institute
28-Oct-2002


Page: 1 2

Related medicine news :

1. Studies underscore genetic involvement in nicotine addiction & aggressive hostility
2. Brain activity of men and women during hostile or impulsive acts differs less on nicotine
3. Animal study shows link between nicotine and atrial flutter
4. Free nicotine patches increase short-term smoking quit rates
5. Brains nicotine receptors also target for anti-depressants
6. Antidepressant may help people stop smoking when used with nicotine patch
7. Majority of cigarettes in the US smoked by nicotine-dependent or psychiatrically ill persons
8. Reduced exposure tobacco products lessen carcinogen exposure, but medicinal nicotine better
9. Success of nicotine patches linked to genetic make-up
10. Study supports new theory for nicotines protective effect against neurodegenerative disorders
11. Minors able to buy nicotine replacement therapy products

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: nicotine product reacts with proteins say scientists TSRI

(Date:4/27/2015)... Churchview Supportive Living, a Gardant affordable assisted living community, ... from 10:30 a.m. to noon on May 8. , ... St. in Chicago, serves low-income older adults, including those ... independence. , “Mothers, grandmothers, godmothers and mothers-to-be are invited ... Director of Marketing Elizabeth Clippard. , The menu will ...
(Date:4/27/2015)... 2015 Medical Device Design Control , ... Ombu Enterprises**, June 16-17, 2015 – Chicago, IL , ... to a facility today, would the design control system ... is "maybe" or "no" … then very likely there ... a solution. , Take this important step. Enroll ...
(Date:4/27/2015)... How to Implement UDI:, Lessons from Early ... – 3:00 p.m. EDT, http://www.fdanews.com/HowToImplementUDI , With ... restraint, there’s plenty of time to get ready for ... deadlines are coming fast for all devicemakers and soon ... even if it seems there’s no rush. It's already ...
(Date:4/27/2015)... NY (PRWEB) April 28, 2015 ... new white paper called “Website Anatomy 101.” ... paper discusses the necessary design elements for a ... emphasis on responsive design, user experience, search results ... the impact of a well-designed website on patient ...
(Date:4/27/2015)... (PRWEB) April 27, 2015 Women may ... from concussion, according to a new study published online ... mild traumatic brain injury (MTBI), is a common medical ... some individuals. , In most cases, patients who ... Ten to 15 percent of MTBI patients will continue ...
Breaking Medicine News(10 mins):Health News:Churchview Supportive Living Community in Chicago to Host Mother's Day Brunch 2Health News:FDAnews Announces: Medical Device Design Control: Implementing an Approach That Works, June 16-17, Chicago, IL 2Health News:FDAnews Announces: Medical Device Design Control: Implementing an Approach That Works, June 16-17, Chicago, IL 3Health News:FDAnews Announces: Medical Device Design Control: Implementing an Approach That Works, June 16-17, Chicago, IL 4Health News:FDAnews Announces: How to Implement UDI: Lessons from Early Adopters Webinar, May 20, 2015 2Health News:FDAnews Announces: How to Implement UDI: Lessons from Early Adopters Webinar, May 20, 2015 3Health News:Smith & Jones Publishes 2015 Website Design White Paper 2Health News:Women Show Persistent Memory Impairment after Concussion 2Health News:Women Show Persistent Memory Impairment after Concussion 3
(Date:4/27/2015)...  Together with its parent partners and the Community ... initiative of Morris County Prevention is Key (MCPIK), the ... community effort to address the heroin/opiate crisis in ... Volunteer Parent Coaches from the Partnership, ... Denise Mariano , National Council on Alcoholism and Drug ...
(Date:4/27/2015)... 2015 PAML announced today that the ... Axela, Inc. to develop multiplex assays focused on ... of the nation,s leading medical reference laboratories, and ... analysis for clinical diagnostics. Axela,s ... assay development serves as the foundation for novel ...
(Date:4/27/2015)... Calif. , April 27, 2015  Eiger BioPharmaceuticals, ... Phase 2 data of lonafarnib in patients with chronic ... the LOWR HDV program, enrolled at Ankara University Medical ... where HDV is endemic. LOWR HDV ... parallel dose comparison study which randomized subjects to receive ...
Breaking Medicine Technology:Partnership for Drug-Free Kids Brings Life-Saving Kits and Training to New Jersey Families 2Partnership for Drug-Free Kids Brings Life-Saving Kits and Training to New Jersey Families 3PAML and Axela Collaborate on Immune Status for Vaccine Preventable Diseases 2Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 2Eiger Bio Announces Interim Results of Lonafarnib in Combination with Ritonavir or Pegylated Interferon in Patients Infected with Hepatitis Delta Virus (HDV) 3
Cached News: