HOME >> MEDICINE >> NEWS
ACE-Inhibitors Score High In Reducing Heart Attack Deaths

DALLAS, June 9 -- A type of drug that lowers high blood pressure improves a person's odds of surviving after a heart attack, say researchers reporting on a study of nearly 100,000 heart attack patients that appears in today's Circulation: Journal of the American Heart Association.

The drugs, called an ACE (angiotensin-converting enzyme) inhibitors, interfere with the body's production of a chemical called angiotensin that causes the blood vessels to constrict. When blood vessels widen, blood pressure is lowered. The study found that for every 1,000 individuals treated, five lives were saved after 30 days, says Maria Grazia Franzosi, Ph.D., a pharmacologist at the Istituto di Ricerche Farmacologiche "Mario Negri" in Milan, Italy, who led the collaborative analysis.

"For most individuals, ACE-inhibitor therapy may be started immediately -- during the first few hours of a heart attack," she says. "Most of the benefit appears early, in the first few days, when the risk of death is highest." In an accompanying editorial in the journal, Marc A. Pfeffer, M.D., Ph.D., of the cardiovascular division of Brigham and Women's Hospital at Harvard Medical School in Boston, writes, "ACE-inhibitors have earned their place" along with aspirin and drugs such as beta-blockers and thrombolytic therapies proven to reduce deaths from heart attack.

Thrombolytic, or "clot-busters" and aspirin break up blood clots that can obstruct the blood vessels leading to the heart, while beta-blockers and ACE-inhibitors relax the blood vessels.

On the downside, ACE-inhibitors nearly doubled the risk of low-blood pressure episodes. The rate of such episodes was 17.6 percent in the drug-treated group and 9.3 percent in the control group of patients who were not treated with the drug. Those taking the drug also had double the rate of kidney problems: 1.3 percent in the drug group versus 0.6 percent in controls. The researchers lack data on whether those conditions improved when trea
'"/>

Contact: Carole Bullock
caroleb@amhrt.org
214-706-1279
American Heart Association
8-Jun-1998


Page: 1 2 3

Related medicine news :

1. HeartScore launch - Press teleconference invitation
2. HeartScore(R): New tool for cardiovascular disease risk prediction and management
3. Prenatal Cocaine Exposure Leads To Lower Child IQ Scores, Language Skills
4. Keeping Score On Doctors: Report Says Flaws In Counting Must Be Addressed To Ensure Accuracy
5. Reducing hostility in young coronary artery disease patients is important piece of rehabilitation
6. Reducing anti-rejection meds after transplant shows less complications
7. Reducing the number of walk-in patients wont help solve emergency department overcrowding: Study
8. Reducing side effects of retinoic acid cancer treatment
9. Reducing hypertension in the elderly leads to a significant reduction in the incidence of stroke
10. Reducing antiepileptics in VNS (TM) patients does not impair seizure control
11. Reducing postoperative nausea and vomiting

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: