HOME >> MEDICINE >> NEWS
Actonel helped preserve bone quality at five years, new data show

MINNEAPOLIS (September 22, 2003) Actonel (risedronate sodium tablets) helped preserve important aspects of bone quality at five years in postmenopausal women with osteoporosis, according to new research presented at the 25th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR).

"Studies suggest that bone quality may be an important contributor to bone strength and fracture resistance. These new data provide value in learning how therapies such as risedronate affect bone quality," said principal investigator Eleftherios P. Paschalis, PhD, Ludwig Boltzmann Institute for Osteology, Vienna. "However, additional studies are necessary to fully understand how the different aspects of bone quality relate to fracture risk."

One aspect of bone quality is the integrity of the material components of bone. Bone is a living tissue composed of calcium-based mineral crystals that are embedded in a network of protein fibers, called collagen. In osteoporotic bone, the calcium-based mineral crystals enlarge and the integrity of the collagen deteriorates compared to what is found in normal bone. Actonel, as shown in study biopsies, maintained the size of the calcium crystals and the integrity of the collagen structure over five years of treatment. Actonel is the only osteoporosis therapy for which these aspects of bone quality have been evaluated in bone biopsies taken from the same patients before and after five years of treatment.

About the Study
The study analyzed paired iliac crest biopsies from eight postmenopausal women with osteoporosis who received Actonel (5mg/day) over a 5-year period. The biopsies were analyzed with a novel imaging technique called Fourier Transform Infrared Spectroscopic Imaging (FTIRI), which provides microscopic information on the size of the calcium-based mineral crystals (crystallinity) and the structure of the collagen (collagen cross-link ratio, pyr/deH-DHLNL).

Biopsies
'"/>


22-Sep-2003


Page: 1 2 3 4 5

Related medicine news :

1. Actonel reduced nonveterbral fracture as early as 6 months
2. New analysis shows early intervention with Actonel reduces first vertebral fracture risk
3. FDA approves Actonel for once-a-week use
4. Study shows Actonel reduces vertebral fracture risk 70 percent in patients on chronic steroid therapy
5. Has cricket helped to unite South Asia?
6. Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control
7. Media focus on endostatin helped -- not hurt --
8. Burnout patients helped by comparisons with colleagues
9. Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
10. Doctors transplant ovary to womans arm to preserve fertility
11. Physical activity in later years helps women preserve functional abilities

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Actonel helped preserve bone quality five years new data show

(Date:7/7/2015)... ... July 07, 2015 , ... Dr. Poneh Ghasri ... whitening treatments. A professional teeth whitening is one of the fastest, easiest ways to ... as they can decrease smile satisfaction and confidence. With the right teeth whitening treatment, ...
(Date:7/7/2015)... CA (PRWEB) , ... July 07, 2015 , ... America ... others. California Casualty’s Nominate A Hero program offers a special way to ... a well-deserving hero receives a $250 gift card and their place on the “Wall ...
(Date:7/7/2015)... ... July 07, 2015 , ... Office ... the company’s new Chief Financial Officer, effective July 6th, 2015. Ellen joins Office ... ranging from a multi-billion dollar, global chemical company to early and growth-stage technology ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... motivated leaders with strong managerial expertise to oversee large healthcare operations and ... staff, providers, business partners, insurance companies, and regulators. American Sentinel University, an ...
(Date:7/7/2015)... IL (PRWEB) , ... July ... ... Inc., a leading provider of unified communication management solutions, has announced the ... Infortel® Select. , This service pack includes a number of enhancements to ...
Breaking Medicine News(10 mins):Health News:Los Angeles Cosmetic Dentist, Poneh Ghasri DDS, Now Offers Promotions on Whitening Treatments 2Health News:Los Angeles Cosmetic Dentist, Poneh Ghasri DDS, Now Offers Promotions on Whitening Treatments 3Health News:California Casualty Wants to Know: "Who Is Your Hero?" 2Health News:Office Practicum Announces new CFO 2Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 2Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 3Health News:American Sentinel University Details Six Ways Healthcare Leaders Can Sharpen Communications Skills 4Health News:ISI Telemanagement Solutions, Inc. Releases Service Pack 5600 for Infortel® Select 2
(Date:7/7/2015)... , July 7, 2015  Essentialis, a venture-backed company ... for the treatment of orphan neurobehavioral and metabolic diseases, today ... CSO, will present a corporate update at the Cantor Fitzgerald ... Date: Wednesday, July 8, 2015 Time: 8:00 ... About Essentialis, Inc. Essentialis ...
(Date:7/7/2015)... , July 7, 2015 Oramed ... a clinical-stage pharmaceutical company focused on the development of ... signed a non-binding Letter of Intent (LoI) for an ... with Sinopharm Capital Management Co. Ltd. and Hefei ... Ltd. (Sinopharm/ Hefei ) potentially valued at ...
(Date:7/6/2015)... July 6, 2015  Student-athletes at community colleges ... from a recently established partnership between ImPACT Applications, ... . The partnership enables member institutions of ... ImPACT ® concussion baseline and post-injury testing ... of community colleges in California ...
Breaking Medicine Technology:Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 2Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 3Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 4Sinopharm Capital-Hefei Signs Letter of Intent with Oramed for $50,000,000 Investment and Licensing Deal in China 5California Community College Athletic Departments to Benefit from ImPACT Concussion Baseline Testing Offered by Student Insurance 2California Community College Athletic Departments to Benefit from ImPACT Concussion Baseline Testing Offered by Student Insurance 3
Cached News: