HOME >> MEDICINE >> NEWS
Actonel helped preserve bone quality at five years, new data show

MINNEAPOLIS (September 22, 2003) Actonel (risedronate sodium tablets) helped preserve important aspects of bone quality at five years in postmenopausal women with osteoporosis, according to new research presented at the 25th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR).

"Studies suggest that bone quality may be an important contributor to bone strength and fracture resistance. These new data provide value in learning how therapies such as risedronate affect bone quality," said principal investigator Eleftherios P. Paschalis, PhD, Ludwig Boltzmann Institute for Osteology, Vienna. "However, additional studies are necessary to fully understand how the different aspects of bone quality relate to fracture risk."

One aspect of bone quality is the integrity of the material components of bone. Bone is a living tissue composed of calcium-based mineral crystals that are embedded in a network of protein fibers, called collagen. In osteoporotic bone, the calcium-based mineral crystals enlarge and the integrity of the collagen deteriorates compared to what is found in normal bone. Actonel, as shown in study biopsies, maintained the size of the calcium crystals and the integrity of the collagen structure over five years of treatment. Actonel is the only osteoporosis therapy for which these aspects of bone quality have been evaluated in bone biopsies taken from the same patients before and after five years of treatment.

About the Study
The study analyzed paired iliac crest biopsies from eight postmenopausal women with osteoporosis who received Actonel (5mg/day) over a 5-year period. The biopsies were analyzed with a novel imaging technique called Fourier Transform Infrared Spectroscopic Imaging (FTIRI), which provides microscopic information on the size of the calcium-based mineral crystals (crystallinity) and the structure of the collagen (collagen cross-link ratio, pyr/deH-DHLNL).

Biopsies
'"/>


22-Sep-2003


Page: 1 2 3 4 5

Related medicine news :

1. Actonel reduced nonveterbral fracture as early as 6 months
2. New analysis shows early intervention with Actonel reduces first vertebral fracture risk
3. FDA approves Actonel for once-a-week use
4. Study shows Actonel reduces vertebral fracture risk 70 percent in patients on chronic steroid therapy
5. Has cricket helped to unite South Asia?
6. Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control
7. Media focus on endostatin helped -- not hurt --
8. Burnout patients helped by comparisons with colleagues
9. Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
10. Doctors transplant ovary to womans arm to preserve fertility
11. Physical activity in later years helps women preserve functional abilities

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Actonel helped preserve bone quality five years new data show

(Date:3/30/2015)... This report studies the global pharmacovigilance and drug ... 2014 to 2019. This market is expected to ... to 2019. , Further Inquiry @ http://www.marketsandmarkets.com/Enquiry_Before_Buying.asp?id=16831714 ... and drug safety software market has been classified ... namely, adverse event reporting software, drug safety audits ...
(Date:3/30/2015)... New York, New York (PRWEB) March 30, 2015 ... of its Top 10 Exotic Water Awards, with the top ... other winners are listed on the company’s website, along with ... Water’s website, exotic water, glacial water, spring water, mineral water ... Fiji water is one of the top exotic water ...
(Date:3/30/2015)... FMC Corporation’s Health and Nutrition division ... Epax® Ultra and Core concentrates manufactured in the ... ensures the manufacturing process and all physical raw ... for Halal. , The new Halal certification ... advance its customer service to a global market ...
(Date:3/30/2015)... Slidezilla, an app from the makers of ... innovates the fun and simplicity of photo slideshows. The ... slideshows and then instantly share them across their Facebook, ... to create a slideshow app where users can share ... options to personalize them. You can choose your own ...
(Date:3/30/2015)... V/NO (Virtually No Alcohol) Wines have a sleek ... and for reuse. Consumers simply twist the cup, turn it ... professionals, and basically anyone can now enjoy a non-alcoholic ... socially or pair with meals at work, home, or wherever ... and that means Napa Wine grapes undergo the traditional ...
Breaking Medicine News(10 mins):Health News:The Global Pharmacovigilance and Drug Safety Software Market is Poised to reach the Value of $154.1 Million in 2019 - Report by MarketsandMarkets 2Health News:The Global Pharmacovigilance and Drug Safety Software Market is Poised to reach the Value of $154.1 Million in 2019 - Report by MarketsandMarkets 3Health News:The Global Pharmacovigilance and Drug Safety Software Market is Poised to reach the Value of $154.1 Million in 2019 - Report by MarketsandMarkets 4Health News:Best Exotic Water Brands Acclaimed by 10 Best Water 2Health News:FMC Health and Nutrition Announces Halal Certification for Epax® Brand Omega-3 Ingredients 2Health News:Napa Valley Alcohol-Removed Red, White & Rosé Wines Have Launched. 2
(Date:3/30/2015)... March 30, 2015   GlassesUSA , the online retailer ... $12.5 million in new financing led by Viola Private ... will further GlassesUSA,s aggressive business growth and accelerate their expansion ... online eyewear, both B2C and B2B. GlassesUSA was ... Eldad Rothman , and CTO Roy Yamner . ...
(Date:3/30/2015)... HA,AYIN, Israel , March 30, 2015 ... of Dr. Yuval Avni as the company,s ... partner at Giza VC, a leading early stage Israeli ... with clinical experience in general and vascular surgery.   ... company also announced today that Sherpa Innoventures is Beta-O2,s ...
(Date:3/30/2015)... Pharmaceuticals Corporation (NASDAQ: RXII ), a biotechnology ... primarily in the areas of dermatology and ophthalmology ... financial results for the fourth quarter and year ... update. Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ... a steady growth and evolution for RXi Pharmaceuticals," ...
Breaking Medicine Technology:GlassesUSA.com Raises $12.5 Million Growth Round Led By Viola Private Equity 2GlassesUSA.com Raises $12.5 Million Growth Round Led By Viola Private Equity 3Beta-O2 Names Dr. Yuval Avni CEO 2Beta-O2 Names Dr. Yuval Avni CEO 3RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 2RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 3RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 4RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 5RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 6RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 7RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 8RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 9RXi Pharmaceuticals Reports Fourth Quarter and Year End 2014 Financial Results and Recent Corporate Highlights 10
Cached News: