HOME >> MEDICINE >> NEWS
Actonel helped preserve bone quality at five years, new data show

MINNEAPOLIS (September 22, 2003) Actonel (risedronate sodium tablets) helped preserve important aspects of bone quality at five years in postmenopausal women with osteoporosis, according to new research presented at the 25th Annual Meeting of the American Society for Bone and Mineral Research (ASBMR).

"Studies suggest that bone quality may be an important contributor to bone strength and fracture resistance. These new data provide value in learning how therapies such as risedronate affect bone quality," said principal investigator Eleftherios P. Paschalis, PhD, Ludwig Boltzmann Institute for Osteology, Vienna. "However, additional studies are necessary to fully understand how the different aspects of bone quality relate to fracture risk."

One aspect of bone quality is the integrity of the material components of bone. Bone is a living tissue composed of calcium-based mineral crystals that are embedded in a network of protein fibers, called collagen. In osteoporotic bone, the calcium-based mineral crystals enlarge and the integrity of the collagen deteriorates compared to what is found in normal bone. Actonel, as shown in study biopsies, maintained the size of the calcium crystals and the integrity of the collagen structure over five years of treatment. Actonel is the only osteoporosis therapy for which these aspects of bone quality have been evaluated in bone biopsies taken from the same patients before and after five years of treatment.

About the Study
The study analyzed paired iliac crest biopsies from eight postmenopausal women with osteoporosis who received Actonel (5mg/day) over a 5-year period. The biopsies were analyzed with a novel imaging technique called Fourier Transform Infrared Spectroscopic Imaging (FTIRI), which provides microscopic information on the size of the calcium-based mineral crystals (crystallinity) and the structure of the collagen (collagen cross-link ratio, pyr/deH-DHLNL).

Biopsies
'"/>


22-Sep-2003


Page: 1 2 3 4 5

Related medicine news :

1. Actonel reduced nonveterbral fracture as early as 6 months
2. New analysis shows early intervention with Actonel reduces first vertebral fracture risk
3. FDA approves Actonel for once-a-week use
4. Study shows Actonel reduces vertebral fracture risk 70 percent in patients on chronic steroid therapy
5. Has cricket helped to unite South Asia?
6. Treatment helped reduce dose of inhaled corticosteroids while maintaining asthma control
7. Media focus on endostatin helped -- not hurt --
8. Burnout patients helped by comparisons with colleagues
9. Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
10. Doctors transplant ovary to womans arm to preserve fertility
11. Physical activity in later years helps women preserve functional abilities

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Actonel helped preserve bone quality five years new data show

(Date:4/27/2015)... A new type of festival is emerging in Richmond’s craft ... the Science Museum of Virginia not only fills your cup ... a bold, new flavor. , The 21+ festival hosts local ... behind these frothy beverages. Guests uncover the brewing process with ... that go into beer with Original Gravity and discover the ...
(Date:4/27/2015)... "Understanding Mental Disorders: Your Guide to ... American Psychiatric Publishing, a division of the American Psychiatric ... the National Press Club in Washington, D.C.. The launch ... APA President Paul Summergrad, MD. Guest speakers will include ... to the book; Paul Gionfriddo, President and CEO of ...
(Date:4/27/2015)... Md. (PRWEB) April 27, 2015 On May ... ones will ask their social media friends around the world ... dismissed as asthma. , May 5 is World Pulmonary ... (PHA), a leader in the global PH community, will take ... or high blood pressure of the lungs. PH is an ...
(Date:4/27/2015)... NC (PRWEB) April 27, 2015 According ... Dental and Craniofacial Research), after chronic back pain, TMJ ... conditions resulting in pain and disability. In addition, the ... 12 percent of the population, costing an estimated 4 ... 10 million Americans suffering from seemingly unrelated symptoms such ...
(Date:4/27/2015)... Hamilton, NJ (PRWEB) April 27, 2015 ... information security management standard for companies of all sizes ... a leader in helping companies prepare for ISO 27001 ... dozens of clients to prepare them for ISO 27001 ... than ever, as evidenced by the number of Lead ...
Breaking Medicine News(10 mins):Health News:Science on Tap at the Science Museum of Virginia 2Health News:American Psychiatric Association, Patrick Kennedy To Debut New Consumer Guidebook “Understanding Mental Disorders” 2Health News:Pulmonary Hypertension Association Marks World PH Day on May 5 with a Worldwide Lifesaving Social Media Blitz 2Health News:Pulmonary Hypertension Association Marks World PH Day on May 5 with a Worldwide Lifesaving Social Media Blitz 3Health News:Dentist in Graham NC Reveals that a Jaw Disorder May Be the Cause of Chronic Headaches and Back Pain 2Health News:Six Additional New ISO 27001 Lead Implementers Certified for Pivot Point Security 2
(Date:4/27/2015)... SANTA MONICA, Calif. , April 27, 2015 ... committee for passing a bill that requires prescribers ... most addictive medications – like OxyContin and other ... and thousands of overdose deaths. SB ... D- Bell Gardens , will require ...
(Date:4/27/2015)... 2015  Recognizing the unique position Massachusetts ... the most respected organizations in the New England medtech community, ... Industry Council (MassMEDIC), have partnered to celebrate the region,s ... Annual Massachusetts Medtech Week. This celebration will take place May ... Center in Boston . For more information ...
(Date:4/27/2015)... April 27, 2015 Boston Scientific Corporation ... Brainlab AG, a leading software-driven medical technology company ... navigation. The collaboration provides patients and physicians a ... DBS is intended to treat a variety of ... for movement disorders such as Parkinson,s disease (PD), ...
Breaking Medicine Technology:Consumer Watchdog Praises Passage of Bill that Requires Physicians Check Prescription Drug Database Before Prescribing Powerful, Addictive Medications 2Consumer Watchdog Praises Passage of Bill that Requires Physicians Check Prescription Drug Database Before Prescribing Powerful, Addictive Medications 3First Annual Massachusetts Medtech Week Celebrated this May 2First Annual Massachusetts Medtech Week Celebrated this May 3Boston Scientific Announces Strategic Collaboration With Brainlab AG 2Boston Scientific Announces Strategic Collaboration With Brainlab AG 3Boston Scientific Announces Strategic Collaboration With Brainlab AG 4
Cached News: