HOME >> MEDICINE >> NEWS
African-American women with endometrial cancer have more aggressive cancer than Caucasian women

Miami, March 21, 2005--In two studies of African-American women with endometrial cancer, a group of investigators from Walter Reed Army Medical Center and the National Cancer Institute has found that African-American women with advanced endometrial cancer have more aggressive tumors than Caucasian women, potentially leading to worse outcomes.

Specifically, the investigators first performed a retrospective study of data from four treatment trials carried out by the Gynecologic Oncology Group (GOG) in a clinical trial setting where patients receive similar care, to determine if outcomes remain poor for African-American women with endometrial cancer. The GOG is an NCI-funded national cooperative group that coordinates most of the large therapeutic gynecologic cancer studies in the U.S.

In this study, the survival rates for 168 African-American patients and 997 Caucasian patients with Stage III, Stage IV or recurrent endometrial cancer were analyzed and compared. This analysis showed that African-American women with advanced endometrial cancer have a 25 percent greater chance of dying than Caucasian patients with the same diagnosis, even in the setting of a controlled clinical trial.

Based on the clinical data from the GOG study, the investigators hypothesized that there may be biologic differences in endometrial cancers in African-American women compared to Caucasian women that lead to more aggressive tumors. The investigators subsequently performed a study evaluating global gene expression among patients with advanced endometrial cancer using tumor samples from patients treated at Duke University Medical Center.

Cancers from 18 African-American patients were compared to those from 27 Caucasian patients who were matched according to stage, grade and cell type.

It was found that distinct and different patterns of gene expression may characterize advanced endometrial cancers in African-American and Caucasian women, and
'"/>

Contact: Sarah Handza
202-441-3712
Society of Gynecologic Oncologists
22-Mar-2005


Page: 1 2 3

Related medicine news :

1. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
2. Obesity among African-American stroke survivors increases risk factors for recurrent stroke
3. African-Americans receive less aggressive heart attack treatment
4. African-Americans may need more medication to control asthma
5. Good medicine, good economics: African-Americans need equal treatment for pain, SLU study finds
6. Beliefs may hinder HIV prevention among African-Americans
7. Study suggests obesity has lesser financial impact on African-Americans
8. Sobering disparity: African-Americans receive less compensation for job-related back injuries
9. African-American heart attack patients fare worse long term
10. New Crestor data in African-American patients with high cholesterol
11. New medication dramatically decreases congestive heart failure in African-American patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... Little Rock, AR (PRWEB) , ... October 13, ... ... owned firm with locations throughout Arkansas that offers insurance and financial preparation services, ... to benefit the Rock City Rescue organization. , Rock City Rescue is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading ... Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly ... CBD form that can be easily incorporated into liquid products, while reducing costs to ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  True Health, a ... amplified its effort during National Breast Cancer Awareness ... cancer risks. ... Oncology calculated that more than 10 million American ... mutations in BRCA1 or BRCA2 and have not had ...
(Date:10/10/2017)... COUNTY, Calif. , Oct. 10, 2017  NDS received FDA ... Mobile  — a medical-grade battery-powered display stand specifically designed for endoscopy ... to transform technology into a clinical solution to support the improvement ... Innovative Design ... ZeroWire Mobile Wireless Solution ...
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
Breaking Medicine Technology:
Cached News: