HOME >> MEDICINE >> NEWS
African-American women with endometrial cancer have more aggressive cancer than Caucasian women

Miami, March 21, 2005--In two studies of African-American women with endometrial cancer, a group of investigators from Walter Reed Army Medical Center and the National Cancer Institute has found that African-American women with advanced endometrial cancer have more aggressive tumors than Caucasian women, potentially leading to worse outcomes.

Specifically, the investigators first performed a retrospective study of data from four treatment trials carried out by the Gynecologic Oncology Group (GOG) in a clinical trial setting where patients receive similar care, to determine if outcomes remain poor for African-American women with endometrial cancer. The GOG is an NCI-funded national cooperative group that coordinates most of the large therapeutic gynecologic cancer studies in the U.S.

In this study, the survival rates for 168 African-American patients and 997 Caucasian patients with Stage III, Stage IV or recurrent endometrial cancer were analyzed and compared. This analysis showed that African-American women with advanced endometrial cancer have a 25 percent greater chance of dying than Caucasian patients with the same diagnosis, even in the setting of a controlled clinical trial.

Based on the clinical data from the GOG study, the investigators hypothesized that there may be biologic differences in endometrial cancers in African-American women compared to Caucasian women that lead to more aggressive tumors. The investigators subsequently performed a study evaluating global gene expression among patients with advanced endometrial cancer using tumor samples from patients treated at Duke University Medical Center.

Cancers from 18 African-American patients were compared to those from 27 Caucasian patients who were matched according to stage, grade and cell type.

It was found that distinct and different patterns of gene expression may characterize advanced endometrial cancers in African-American and Caucasian women, and
'"/>

Contact: Sarah Handza
202-441-3712
Society of Gynecologic Oncologists
22-Mar-2005


Page: 1 2 3

Related medicine news :

1. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
2. Obesity among African-American stroke survivors increases risk factors for recurrent stroke
3. African-Americans receive less aggressive heart attack treatment
4. African-Americans may need more medication to control asthma
5. Good medicine, good economics: African-Americans need equal treatment for pain, SLU study finds
6. Beliefs may hinder HIV prevention among African-Americans
7. Study suggests obesity has lesser financial impact on African-Americans
8. Sobering disparity: African-Americans receive less compensation for job-related back injuries
9. African-American heart attack patients fare worse long term
10. New Crestor data in African-American patients with high cholesterol
11. New medication dramatically decreases congestive heart failure in African-American patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... PurhealthRX , a leading Health and Nutrition Company, is announcing the ... spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the amount ... into liquid products, while reducing costs to end users. , The team of researchers ...
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... 2017 , ... Coveros, a leader in agile coaching services ... by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile Transformation ... Agile methodologies in a consistent and high value manner across CMS programs. Coveros ...
(Date:10/12/2017)... Orleans, LA (PRWEB) , ... October 12, 2017 , ... ... centers in the U.S., announced today its plans to open a flagship location in ... will occupy the former Rooms To Go store next to Office Depot in the ...
(Date:10/12/2017)... ... 2017 , ... Information about the technology: , Otomagnetics has ... prevention of a major side effect of chemotherapy in children. Cisplatin and carboplatin ... cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. Hearing ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading ... announced that its MyDario product is expected to appear on The Dr. ... The Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show ... The segment ...
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
(Date:9/13/2017)... , Sept. 13, 2017   OrthoAtlanta has ... the Atlanta Football Host Committee (AFHC) for the 2018 College ... Jan. 8, 2018, at Mercedes-Benz Stadium in Atlanta, ... of the AFHC "I,m In" campaign, participating in many activities ... ...
Breaking Medicine Technology:
Cached News: