Alcohol use increases the risk of hormonally sensitive breast cancers in postmenopausal women

SEATTLE - Older women with a history of alcohol use are significantly more likely than nondrinkers to be diagnosed with hormonally sensitive forms of breast cancer, including lobular carcinomas and estrogen-receptor positive (ER+) and progesterone-receptor positive (PR+) tumors, according to researchers at Fred Hutchinson Cancer Research Center.

Lead author Christopher I. Li, M.D., Ph.D., and colleagues report their findings in the October issue of Cancer Epidemiology, Biomarkers and Prevention.

"Women who were current drinkers who reported consuming at least 30 grams of alcohol a day - roughly the equivalent of two drinks - had an 80 percent higher risk of breast cancer compared to nondrinkers," said Li, an assistant member of Fred Hutchinson's Public Health Sciences Division.

The risk varied by cellular, or histologic, breast-cancer type. "Current consumers of two or more drinks per day had more than three times the risk of lobular cancer (a 330 percent increased risk) and a 50 percent increased risk of ductal cancer," Li said.

While lobular breast cancer, which involves the lobules, or chambers in the breast that contain milk-producing glands, accounts for only 10 percent to 15 percent of all breast-cancer cases, its incidence is on the rise. Li and colleagues earlier this year reported a 65 percent increase in lobular cancer during the past decade, a trend that may be due to the increased use of combined estrogen and progestin hormone-replacement therapy, Li said (Journal of the American Medical Association, March 19, 2003).

Ductal breast cancer, which involves the ducts that carry milk from the lobules to the nipple, accounts for about 80 percent of cases. The incidence of this form of breast cancer has remained essentially constant during the past decade.

While somewhat more difficult to diagnose than ductal breast cancers, lobular carcinomas tend to be ER+ and PR+, which means they are more responsive to hormonal therapies such a

Contact: Kristen Woodward
Fred Hutchinson Cancer Research Center

Page: 1 2 3

Related medicine news :

1. Alcohol relapse adversely affects 10-year liver transplant survival
2. Alcohol intervention attempted for violent males
3. Alcohols damaging effects on adolescent brain function
4. Alcohol drinkers three times as likely to die from injury
5. Alcohol: Global burden on health similar to tobacco and high blood pressure
6. Alcoholics can have deficits in visuoperception and frontal executive function despite sobriety
7. RFA safe for treating liver tumors pushing on GI tract; Alcohol injection makes RFA more effective
8. Alcohol consumption may be associated with irregular heart beat in men
9. Alcohol use and victimization among college women
10. Alcohol limit for drink driving should be much lower
11. Alcohol-related emergency department visits higher than previously thought

Post Your Comments:

(Date:8/31/2020)... ... August 31, 2020 , ... ... N95 face masks to medical first responders across the United States. Since the ... of personal protective equipment (PPE) medical centers , hospitals , ...
(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., one of ... United States, today announced the grand opening of another affiliated Bright Now! ... enjoy convenient hours, a comfortable office, and full-service care at the new Beaumont ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... directly with persons with autism and other developmental disabilities, as well as supporting ... parent education, adolescents with autism, school consultation, and staff development. She joined the ...
(Date:8/28/2020)... ... 28, 2020 , ... WHAT , Hespiro™ is a new ... conditions, including COVID-19, while reducing the need for scarce mechanical ventilators. It not ... and scrubs it free of carbon dioxide in a completely closed “rebreather” system, ...
(Date:8/28/2020)... ... August 28, 2020 , ... Ziegler, a specialty investment bank, ... in Synchronous Health, a tech-enabled behavioral health and well-being solutions provider. , ... with artificial intelligence (AI) to increase access and quality of behavioral health services, ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... CONSHOHOCKEN, Pa. (PRWEB) , ... August 27, 2020 ... ... and care coordination software, today announced the successful completion of their 2020 System ... as well as their HITRUST® interim assessment and MARS-E compliance assessment. These achievements ...
(Date:8/27/2020)... , ... August 27, 2020 , ... Bleep LLC, maker ... and sleep apnea patient, is the company’s new spokesperson. , “In my line of ... So, when I found the Bleep DreamPort it was a Bleeping no brainer for ...
(Date:8/27/2020)... ... August 27, 2020 , ... The GHT Companies , ... fundraising initiative for Feeding San Diego with a press conference at its ... presents the final check of $5,000.00+ representing an overall donation result exceeding $30,000 to ...
Breaking Medicine Technology:
Cached News: