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American Academy of Neurology awards 2004 Potamkin Prize to two scientists

ization to identify Vitamin E as an effective therapy for Alzheimer's disease. ACDS research also revealed that estrogen therapy was not effective for treating mild to moderate Alzheimer's disease in women. His current research interests include studying the potential therapeutic benefits of using nerve growth factor as a genetic therapy for Alzheimer's disease. He also continues to oversee clinical drug trials for new and promising Alzheimer's disease therapies through the ADCS.

Nitsch's research has helped revitalized hopes for a vaccination against Alzheimer's disease. Following the halt of a major vaccination trial in 2002, there was serious concern within the neuroscientific community as to whether it was possible to develop an effective and safe vaccine against Alzheimer's disease.

Nitsch's work in experimental immunotherapy has been key to keeping alive the hope that science can find an effective and safe vaccine against Alzheimer's disease. His research produced groundbreaking evidence linking beta-amyloid deposits to the formation of plaque and fiber tangles in the brain, both of which are viewed as contributing to the development of Alzheimer's disease. Working with an experimental vaccine, Nitsch subsequently demonstrated success in generating antibodies to help the brain defend itself against beta-amyloids. The net result was a significant slowing of the pace at which Alzheimer's patients lose cognitive functions and their ability to handle daily living activities.

The Potamkin Prize is made possible by the philanthropic contributions of the Potamkin family of New York, Philadelphia and Miami. The goal of the prize is to help attract the best medical minds and most dedicated scientists in the world to the field of dementia research.


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Contact: Kathy Stone
kstone@aan.com
651-695-2763
American Academy of Neurology
21-Apr-2004


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